The conversion of 6-farnesyl-5,7-dihydroxy-4-methylphthalide (5) into mycophenolic acid (1) proceeds through the hydroxy-ketone (11) by oxidation of the central double bond.
Biosynthesis of mycophenolic acid. Oxidation of 6-farnesyl-5,7-dihydroxy-4- methylphthalide in a cell-free preparation from Penicillium brevicompactum / L. Colombo, C.M.A. Gennari, C. Scolastico. - In: JOURNAL OF THE CHEMICAL SOCIETY, CHEMICAL COMMUNICATIONS. - ISSN 0022-4936. - :10(1978), pp. 434-434. [10.1039/C39780000434]
Biosynthesis of mycophenolic acid. Oxidation of 6-farnesyl-5,7-dihydroxy-4- methylphthalide in a cell-free preparation from Penicillium brevicompactum
C.M.A. Gennari;C. Scolastico
1978
Abstract
The conversion of 6-farnesyl-5,7-dihydroxy-4-methylphthalide (5) into mycophenolic acid (1) proceeds through the hydroxy-ketone (11) by oxidation of the central double bond.File in questo prodotto:
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