Male pseudohermaphroditism is a sex differentiation disorder in which the gonads are testes and the genital ducts are incompletely masculinized. An 8 years old dog with normal male karyotype was referred for examination of external genitalia abnormalities. Adjacent to the vulva subcutaneous undescended testes were observed. The histology of the gonads revealed a Leydig and Sertoli cell neoplasia. The contemporaneous presence of testicular tissue, vulva, male karyotype were compatible with a male pseudohermaphrodite (MPH) condition.
Clinical, genetic, and pathological features of male pseudohermaphroditism in dog / E. Bigliardi, P. Parma, P. Peressotti, L. De Lorenzi, P. Wohlsein, B. Passeri, S. Jottini, A.M. Cantoni. - In: REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY. - ISSN 1477-7827. - 9(2011), pp. 12.12.1-12.12.7. [10.1186/1477-7827-9-12]
Clinical, genetic, and pathological features of male pseudohermaphroditism in dog
P. ParmaSecondo
;L. De Lorenzi;
2011
Abstract
Male pseudohermaphroditism is a sex differentiation disorder in which the gonads are testes and the genital ducts are incompletely masculinized. An 8 years old dog with normal male karyotype was referred for examination of external genitalia abnormalities. Adjacent to the vulva subcutaneous undescended testes were observed. The histology of the gonads revealed a Leydig and Sertoli cell neoplasia. The contemporaneous presence of testicular tissue, vulva, male karyotype were compatible with a male pseudohermaphrodite (MPH) condition.
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