The intestinal microbiota is an ecosystem formed by a variety of ecological niches, made of several bacterial species and a very large amount of strains. The microbiota is in close contact with the intestinal mucosa or epithelial interface which is, after the respiratory area, the largest surface of the body, occupying approximately 250-400 m(2). The physiological activities of the microbiota are manifold and are just being unraveled. Based on the observations of the multiple roles played by the microbiota in health and disease, the notion of modifying it with appropriate formulations, i.e. probiotics, is being tested in several settings. This review summarizes the current knowledge on probiotics and discusses both limitations and acquired evidence to support their use in preventive and therapeutic medicine.

Probiotics and health : an evidence-based review / P. Aureli, L. Capurso, A.M. Castellazzi, M. Clerici, M. Giovannini, L. Morelli, A. Poli, F. Pregliasco, F. Salvini, G.V. Zuccotti. - In: PHARMACOLOGICAL RESEARCH. - ISSN 1043-6618. - 63:5(2011 May), pp. 366-376. [10.1016/j.phrs.2011.02.006]

Probiotics and health : an evidence-based review

M. Clerici;M. Giovannini;F. Pregliasco;F. Salvini
Penultimo
;
G.V. Zuccotti
Ultimo
2011

Abstract

The intestinal microbiota is an ecosystem formed by a variety of ecological niches, made of several bacterial species and a very large amount of strains. The microbiota is in close contact with the intestinal mucosa or epithelial interface which is, after the respiratory area, the largest surface of the body, occupying approximately 250-400 m(2). The physiological activities of the microbiota are manifold and are just being unraveled. Based on the observations of the multiple roles played by the microbiota in health and disease, the notion of modifying it with appropriate formulations, i.e. probiotics, is being tested in several settings. This review summarizes the current knowledge on probiotics and discusses both limitations and acquired evidence to support their use in preventive and therapeutic medicine.
Immune system; Microbiota; Probiotics
Settore MED/38 - Pediatria Generale e Specialistica
mag-2011
Article (author)
File in questo prodotto:
File Dimensione Formato  
revisione probiotici zuccotti 2011.pdf

accesso aperto

Tipologia: Publisher's version/PDF
Dimensione 269.89 kB
Formato Adobe PDF
269.89 kB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/160162
Citazioni
  • ???jsp.display-item.citation.pmc??? 58
  • Scopus 219
  • ???jsp.display-item.citation.isi??? 170
social impact