A case of AIDS with varicella zoster virus fulminant necrotizing encephalitis associated with cytomegalovirus ependymitis-subependymitis and a periventricular Epstein-Barr virus-related lymphoma is described. The patient had no herpes zoster cutaneous eruptions and died three days after the onset of symptoms. Varicella zoster virus and cytomegalovirus antigens were found by immunohistochemistry in the same area around a necrotic periventricular lesion; a periventricular lymphoma, large B cell type, was also observed. In situ hybridization with Epstein-Barr virus-encoded- RNAs probe was positive in about 40% of the neoplastic cells. The association of herpes-related lesions in the same cerebral region should be consistent in AIDS cases with acute neurological symptoms

VZV fulminant necrotizing encephalitis with concomitant EBV-related lymphoma and CMV ventriculitis: report of an AIDS case / M. Nebuloni, L. Vago, R. Boldorini, S. Bonetto, G. Costanzi. - In: JOURNAL OF NEUROVIROLOGY. - ISSN 1355-0284. - 4:4(1998), pp. 457-460. [10.3109/13550289809114546]

VZV fulminant necrotizing encephalitis with concomitant EBV-related lymphoma and CMV ventriculitis: report of an AIDS case

M. Nebuloni
Primo
;
L. Vago
Secondo
;
G. Costanzi
Ultimo
1998

Abstract

A case of AIDS with varicella zoster virus fulminant necrotizing encephalitis associated with cytomegalovirus ependymitis-subependymitis and a periventricular Epstein-Barr virus-related lymphoma is described. The patient had no herpes zoster cutaneous eruptions and died three days after the onset of symptoms. Varicella zoster virus and cytomegalovirus antigens were found by immunohistochemistry in the same area around a necrotic periventricular lesion; a periventricular lymphoma, large B cell type, was also observed. In situ hybridization with Epstein-Barr virus-encoded- RNAs probe was positive in about 40% of the neoplastic cells. The association of herpes-related lesions in the same cerebral region should be consistent in AIDS cases with acute neurological symptoms
Cytomegalovirus; Encephalitis; Epstein-Barr virus; Human immunodeficiency virus; Varicella tester virus
Settore MED/08 - Anatomia Patologica
Settore MED/17 - Malattie Infettive
1998
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/157708
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