This review compiles results of medical relevance from mitochondrial proteomics, grouped either according to the type of disease - genetic or degenerative - or to the involved mechanism - oxidative stress or apoptosis. The findings are commented in the light of our current understanding of uniformity/variability in cell responses to different stimuli. Specificities in the conceptual and technical approaches to human mitochondrial proteomics are also outlined.
Energy matters: mitochondrial proteomics for biomedicine / E. Gianazza, I. Eberini, C. Sensi, M. Barile, L. Vergani, M.A. Vanoni. - In: PROTEOMICS. - ISSN 1615-9853. - 11:4(2011), pp. 657-674.
Energy matters: mitochondrial proteomics for biomedicine
E. Gianazza
;I. EberiniSecondo
;C. Sensi;M.A. VanoniUltimo
2011
Abstract
This review compiles results of medical relevance from mitochondrial proteomics, grouped either according to the type of disease - genetic or degenerative - or to the involved mechanism - oxidative stress or apoptosis. The findings are commented in the light of our current understanding of uniformity/variability in cell responses to different stimuli. Specificities in the conceptual and technical approaches to human mitochondrial proteomics are also outlined.Pubblicazioni consigliate
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