In chronic heart failure, oxygen delivery during exercise is impaired mainly because of failure of cardiac output to increase normally. Compensatory mechanisms are hemoglobin concentration increase, right-ward shift in the oxyhemoglobin dissociation curve, and blood flow redistribution from the nonexercising organs to the exercising muscles.
Oxygen transport to muscle during exercise in chronic congestive heart failure secondary to idiopathic dilated cardiomyopathy / P. Agostoni, K. Wasserman, G.B. Perego, G.C. Marenzi, M. Guazzi, E. Assanelli, G. Lauri, M.D. Guazzi. - In: THE AMERICAN JOURNAL OF CARDIOLOGY. - ISSN 0002-9149. - 79:8(1997 Apr), pp. 1120-1124.
Oxygen transport to muscle during exercise in chronic congestive heart failure secondary to idiopathic dilated cardiomyopathy
P. Agostoni;M. Guazzi;M.D. Guazzi
1997
Abstract
In chronic heart failure, oxygen delivery during exercise is impaired mainly because of failure of cardiac output to increase normally. Compensatory mechanisms are hemoglobin concentration increase, right-ward shift in the oxyhemoglobin dissociation curve, and blood flow redistribution from the nonexercising organs to the exercising muscles.
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