Purpose of review To evaluate the course of migraine in migraine headache patients undergoing patent foramen ovale (PFO) transcatheter closure. Background Migraine has an important impact on the quality of life, and it seems to be one of the most disabling medical illnesses. In several studies, a high prevalence of right-to-left shunt has been described in patients with migraine, especially migraine with aura. The presence of right-to-left shunt, whatever the mechanism, may be the most potent trigger of migraine attacks in both migraine with aura and migraine without aura and the main determinant of aura in migraine with aura. Methods A cohort of 42 patients (nine men/33 women; mean age 39W11.2 years), current migraineurs, underwent PFO percutaneous closure in our centre between January 2004 and December 2007. All patients rated the severity of their migraine preoperatively and 6 months postoperatively, indicating the frequency, duration, and intensity of the attacks and the occurrence of the aura in the prodromal phase, during the past 6 months, according to the migraine severity score. Results Baseline severity of migraine was higher in migraine with aura patients than in migraine without aura ones (8.8 vs. 7.5; PU0.037). The resolution of migraine was verified in 11 patients (26%) after the closure of the PFO. A reduction in the frequency of the attacks (>– 50%) was

Is it too early to recommend patent foramen ovale closure for all patients who suffer from migraine? A single-centre study / M. Chessa, C. Colombo, G. Butera, D. Negura, L. Piazza, L. Varotto, C. Bussadori, V. Fesslova, G. Meola, M. Carminati. - In: JOURNAL OF CARDIOVASCULAR MEDICINE. - ISSN 1558-2027. - 10:5(2009), pp. 401-405. [10.2459/JCM.0b013e328329caf5]

Is it too early to recommend patent foramen ovale closure for all patients who suffer from migraine? A single-centre study

C. Bussadori;G. Meola;
2009

Abstract

Purpose of review To evaluate the course of migraine in migraine headache patients undergoing patent foramen ovale (PFO) transcatheter closure. Background Migraine has an important impact on the quality of life, and it seems to be one of the most disabling medical illnesses. In several studies, a high prevalence of right-to-left shunt has been described in patients with migraine, especially migraine with aura. The presence of right-to-left shunt, whatever the mechanism, may be the most potent trigger of migraine attacks in both migraine with aura and migraine without aura and the main determinant of aura in migraine with aura. Methods A cohort of 42 patients (nine men/33 women; mean age 39W11.2 years), current migraineurs, underwent PFO percutaneous closure in our centre between January 2004 and December 2007. All patients rated the severity of their migraine preoperatively and 6 months postoperatively, indicating the frequency, duration, and intensity of the attacks and the occurrence of the aura in the prodromal phase, during the past 6 months, according to the migraine severity score. Results Baseline severity of migraine was higher in migraine with aura patients than in migraine without aura ones (8.8 vs. 7.5; PU0.037). The resolution of migraine was verified in 11 patients (26%) after the closure of the PFO. A reduction in the frequency of the attacks (>– 50%) was
Foramen ovale ; migraine
Settore MED/26 - Neurologia
Settore MED/11 - Malattie dell'Apparato Cardiovascolare
2009
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/146447
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