Mobilization of the l-cysteine sulfur for the persulfuration of the rhodanese of Azotobacter vinelandii, RhdA, can be mediated by the A. vinelandii cysteine desulfurases, IscS and NifS. The amount of cysteine was higher in mutant strains lacking rhdA (MV474) than in wild type. The diazotrophic growth of MV474 was impaired. Taking into account the functional results about rhodanese-like proteins and RhdA itself, it is suggested that RhdA-dependent modulation of l-cysteine levels must deal with a redox-related process.

Mobilization of sulfane sulfur from cysteine desulfurases to the Azotobacter vinelandii sulfurtransferase RhdA / F. Cartini, W. Remelli, P.C. Dos Santos, J. Papenbrock, S. Pagani, F. Forlani. - In: AMINO ACIDS. - ISSN 0939-4451. - 41:1(2011 Jun), pp. 141-150. [10.1007/s00726-010-0529-z]

Mobilization of sulfane sulfur from cysteine desulfurases to the Azotobacter vinelandii sulfurtransferase RhdA

F. Cartini
Primo
;
W. Remelli
Secondo
;
S. Pagani
Penultimo
;
F. Forlani
2011

Abstract

Mobilization of the l-cysteine sulfur for the persulfuration of the rhodanese of Azotobacter vinelandii, RhdA, can be mediated by the A. vinelandii cysteine desulfurases, IscS and NifS. The amount of cysteine was higher in mutant strains lacking rhdA (MV474) than in wild type. The diazotrophic growth of MV474 was impaired. Taking into account the functional results about rhodanese-like proteins and RhdA itself, it is suggested that RhdA-dependent modulation of l-cysteine levels must deal with a redox-related process.
RhdA; Sulfurtransferase; Cysteine desulfurase; L-Cysteine; Thiosulfate; Azotobacter vinelandii
Settore BIO/10 - Biochimica
giu-2011
Article (author)
File in questo prodotto:
File Dimensione Formato  
art:10.1007/s00726-010-0529-z.pdf

accesso riservato

Tipologia: Publisher's version/PDF
Dimensione 379.81 kB
Formato Adobe PDF
379.81 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pre_print Mobilization.pdf

accesso aperto

Tipologia: Pre-print (manoscritto inviato all'editore)
Dimensione 438.01 kB
Formato Adobe PDF
438.01 kB Adobe PDF Visualizza/Apri
Post-print Mobilization.pdf

accesso aperto

Tipologia: Post-print, accepted manuscript ecc. (versione accettata dall'editore)
Dimensione 24.48 MB
Formato Adobe PDF
24.48 MB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/143152
Citazioni
  • ???jsp.display-item.citation.pmc??? 7
  • Scopus 12
  • ???jsp.display-item.citation.isi??? 10
social impact