BONFANTI, ELISABETTA
BONFANTI, ELISABETTA
Dipartimento di Scienze Farmacologiche e Biomolecolari
Extracellular vesicles released by microglia and macrophages carry endocannabinoids which foster oligodendrocyte differentiation
2024 M. Lombardi, F. Scaroni, M. Gabrielli, S. Raffaele, E. Bonfanti, F. Filipello, P. Giussani, S. Picciolini, N.K. de Rosbo, A. Uccelli, M.T. Golia, G. D’Arrigo, T. Rubino, K. Hooshmand, C. Legido-Quigley, C. Fenoglio, A. Gualerzi, M. Fumagalli, C. Verderio
Microglial vesicles improve post-stroke recovery by preventing immune cell senescence and favoring oligodendrogenesis
2021 S. Raffaele, P. Gelosa, E. Bonfanti, M. Lombardi, L. Castiglioni, M. Cimino, L. Sironi, M.P. Abbracchio, C. Verderio, M. Fumagalli
Development of the first in vivo GPR17 ligand through an iterative drug discovery pipeline: A novel disease-modifying strategy for multiple sclerosis
2020 C. Parravicini, D. Lecca, D. Marangon, G.T. Coppolino, S. Daniele, E. Bonfanti, M. Fumagalli, L. Raveglia, C. Martini, E. Gianazza, M.L. Trincavelli, M.P. Abbracchio, I. Eberini
Surface Plasmon Resonance as a Tool for Ligand Binding Investigation of Engineered GPR17 Receptor, a G Protein Coupled Receptor Involved in Myelination
2020 D. Capelli, C. Parravicini, G. Pochetti, R. Montanari, C. Temporini, M. Rabuffetti, M.L. Trincavelli, S. Daniele, M. Fumagalli, S. Saporiti, E. Bonfanti, M.P. Abbracchio, I. Eberini, S. Ceruti, E. Calleri, S. Capaldi
Deciphering remyelinating mechanisms induced by clinically-used azole antifungals with exploitable repurposing properties : An in silico approach
2019 U. Guerrini, C. Parravicini, L. Palazzolo, E. Bonfanti, S. Raffaele, T. Laurenzi, M. Fumagalli, F. Di Renzo, R. Bacchetta, E. Menegola, I. Eberini
Improvement of fiber connectivity and functional recovery after stroke by montelukast, an available and safe anti-asthmatic drug
2019 P. Gelosa, E. Bonfanti, L. Castiglioni, J.M. Delgado-Garcia, A. Gruart, L. Fontana, M. Gotti, E. Tremoli, D. Lecca, M. Fumagalli, M. Cimino, L. Aigner, M.P. Abbracchio, L. Sironi
Detrimental and protective action of microglial extracellular vesicles on myelin lesions: astrocyte involvement in remyelination failure
2019 M. Lombardi, R. Parolisi, F. Scaroni, E. Bonfanti, A. Gualerzi, M. Gabrielli, N. Kerlero de Rosbo, A. Uccelli, P. Giussani, P. Viani, C. Garlanda, M.P. Abbracchio, L. Chaabane, A. Buffo, M. Fumagalli, C. Verderio
Deciphering and modelling remyelinating mechanisms induced by clinically-used azole antifungals with exploitable repurposing properties
2018 C. Parravicini, L. Palazzolo, E. Bonfanti, S. Raffaele, T. Laurenzi, M. Fumagalli, U. Guerrini, F. Di Renzo, R. Bacchetta, E. Menegola, I. Eberini
The genetic inhibition of GPR17 affects myelination by influencing important players in oligodendrocyte maturation, including purinergic receptors
2017 D. Lecca, D. Marangon, G. Coppolino, E. Bonfanti, M. Fumagalli, M. Abbracchio
Extracellular vesicles released from microglia-conditioned with mesenchymal stem cells positively regulate oligodendroglial progenitors proliferation in response to focal myelin lesion
2017 R. Parolisi, M. Lombardi, M. Fumagalli, E. Bonfanti, E. Boda, N.K. de Rosbo, A. Uccelli, C. Verderio, A. Buffo
Cross-talk between microglia and oligodendroglial progenitors in cerebral ischemia: implications for new purinergic strategies to brain repair
2017 M. Fumagalli, E. Bonfanti, P. Gelosa, M. Lombardi, L. Dimou, M. Cimino, L. Sironi, C. Verderio, M.P. Abbracchio
Investigating the cross-talk between microglia and oligodendrocyte progenitors in brain ischemia
2017 E. Bonfanti, P. Gelosa, M. Lombardi, M. Cimino, L. Dimou, L. Sironi, C. Verderio, M.P. Abbracchio, M. Fumagalli
Functional roles of extracellular vesicles derived from microglia with diverse activation states
2017 M. Lombardi, I. Prada, R. Parolisi, E. Bonfanti, A. Iorio, P. Joshi, M. Gabrielli, A. Buffo, P. Gressens, M. Fumagalli, C. Verderio
High yield of adult oligodendrocyte lineage cells obtained from meningeal biopsy
2017 D. Sissi, P. Annachiara, B. Valeria, G. Pau, B. Alice, M. Fumagalli, E. Bonfanti, M. Giorgio, P. Francesca, Z. Stefania, A. Clelia, M. Denny, R. Francisco J., F. Guido, F. Bifari, D. Ilaria
Altered expression of the GPR17 receptor in the spinal cord of SOD1G93A mice, a model of amyotrophic lateral sclerosis
2017 M. Fumagalli, E. Bonfanti, T. Bonifacino, M. Milanese, G. Bonanno, M.P. Abbracchio
The role of oligodendrocyte precursor cells expressing the GPR17 receptor in brain remodeling after stroke
2017 E. Bonfanti, P. Gelosa, M. Fumagalli, L. Dimou, F. Viganò, E. Tremoli, M. Cimino, L. Sironi, M.P. Abbracchio
GPR17 expressing NG2-Glia : oligodendrocyte progenitors serving as a reserve pool after injury
2016 F. Viganò, S. Schneider, M. Cimino, E. Bonfanti, P. Gelosa, L. Sironi, M.P. Abbracchio, L. Dimou
New mechanisms regulating myelination in the central nervous system : the role of GPR17 and of a novel micro-RNA
2015 M.P. Abbracchio, M. Fumagalli, D. Marangon, G.T. Coppolino, E. Bonfanti, A. Finardi, D. Lecca, R. Furlan
The ubiquitin ligase Mdm2 controls oligodendrocyte maturation by intertwining mTOR with G protein-coupled receptor kinase 2 in the regulation of GPR17 receptor desensitization
2015 M. Fumagalli, E. Bonfanti, D. Simona, E. Zappelli, D. Lecca, C. Martini, M.L. Trincavelli, M.P. Abbracchio
Microglia-derived extracellular vesicles regulate the proliferation and differentiation of oligodendrocyte precursor cells
2015 M. Fumagalli, M. Lombardi, E. Bonfanti, E. Boda, A. Buffo, M.P. Abbracchio, C. Verderio