IRIS Institutional Research Information System - AIR Archivio Istituzionale della Ricerca

SENECI, PIERFAUSTO
 Distribuzione geografica
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Continente #
EU - Europa 7.516
NA - Nord America 4.244
AS - Asia 3.095
SA - Sud America 269
AF - Africa 41
OC - Oceania 30
Continente sconosciuto - Info sul continente non disponibili 5
Totale 15.200
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Nazione #
US - Stati Uniti d'America 4.181
GB - Regno Unito 2.857
DE - Germania 1.268
CN - Cina 1.258
IT - Italia 1.180
SE - Svezia 626
SG - Singapore 559
TR - Turchia 380
RU - Federazione Russa 361
IN - India 257
KR - Corea 246
IE - Irlanda 240
NL - Olanda 219
FI - Finlandia 191
BR - Brasile 190
FR - Francia 136
UA - Ucraina 126
EU - Europa 97
DK - Danimarca 92
ID - Indonesia 71
HK - Hong Kong 63
CO - Colombia 55
CA - Canada 46
CH - Svizzera 41
BE - Belgio 40
PK - Pakistan 40
JP - Giappone 38
PH - Filippine 36
VN - Vietnam 32
IR - Iran 28
AU - Australia 27
AT - Austria 24
RO - Romania 23
ES - Italia 21
GR - Grecia 20
MY - Malesia 14
PL - Polonia 12
CZ - Repubblica Ceca 10
AE - Emirati Arabi Uniti 9
MX - Messico 9
UZ - Uzbekistan 9
BD - Bangladesh 8
SC - Seychelles 8
TH - Thailandia 8
TW - Taiwan 8
MA - Marocco 7
PT - Portogallo 7
EC - Ecuador 6
AR - Argentina 5
CL - Cile 5
EG - Egitto 5
ZA - Sudafrica 5
BG - Bulgaria 4
DZ - Algeria 4
HU - Ungheria 4
IL - Israele 4
IQ - Iraq 4
KE - Kenya 4
NO - Norvegia 4
OM - Oman 4
TZ - Tanzania 4
CR - Costa Rica 3
KG - Kirghizistan 3
NZ - Nuova Zelanda 3
PY - Paraguay 3
VE - Venezuela 3
A2 - ???statistics.table.value.countryCode.A2??? 2
ET - Etiopia 2
IM - Isola di Man 2
JO - Giordania 2
KZ - Kazakistan 2
LK - Sri Lanka 2
MD - Moldavia 2
PS - Palestinian Territory 2
XK - ???statistics.table.value.countryCode.XK??? 2
AM - Armenia 1
AZ - Azerbaigian 1
BO - Bolivia 1
BS - Bahamas 1
BY - Bielorussia 1
CY - Cipro 1
EE - Estonia 1
HN - Honduras 1
JM - Giamaica 1
KH - Cambogia 1
LA - Repubblica Popolare Democratica del Laos 1
LU - Lussemburgo 1
LV - Lettonia 1
NG - Nigeria 1
PA - Panama 1
PE - Perù 1
QA - Qatar 1
RS - Serbia 1
SA - Arabia Saudita 1
SI - Slovenia 1
SN - Senegal 1
SV - El Salvador 1
TJ - Tagikistan 1
Totale 15.296
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Città #
Southend 2.741
Chandler 521
Milan 456
Frankfurt am Main 428
Seattle 373
Singapore 335
Princeton 302
Wilmington 280
Hanover 251
Beijing 236
Dublin 211
Ashburn 209
Munich 208
Fairfield 187
Council Bluffs 167
Ann Arbor 151
Redmond 148
Dearborn 129
Mountain View 126
Nanjing 125
Woodbridge 123
Des Moines 101
Sakarya 90
Cambridge 89
Houston 85
Bengaluru 77
Helsinki 66
Santa Clara 64
Jacksonville 60
Jinan 58
Shanghai 54
Bogotá 51
Guangzhou 49
Jakarta 46
Boardman 45
Seoul 43
Shenyang 43
Serra 42
Nuremberg 39
Menlo Park 37
Hong Kong 36
Phoenix 36
Cangzhou 35
Brussels 34
Medford 31
Somerville 30
Andover 29
Berlin 29
Hebei 28
Redwood City 28
Nanchang 27
Eitensheim 26
Pune 26
Hangzhou 25
Rome 25
Istanbul 24
Wuhan 24
Zhengzhou 24
New York 23
Multan 22
The Dalles 21
Saint Petersburg 20
San Diego 20
Changsha 19
Fuzhou 19
Bitonto 18
Los Angeles 18
Tianjin 18
Chengdu 17
Rho 17
Toronto 17
Zurich 17
Hefei 16
Jiaxing 15
Melbourne 15
Norwalk 15
Ottawa 14
São Paulo 14
Athens 13
Cremona 13
London 13
Ningbo 13
Silver Spring 13
Taizhou 13
Tehran 13
Xian 13
Fremont 12
Naples 12
Newcastle-under-Lyme 12
Tokyo 12
Boston 11
Falls Church 11
Lappeenranta 11
Mumbai 11
Taiyuan 11
Vienna 11
Grafing 10
Haikou 10
Hamburg 10
Auburn Hills 9
Totale 9.975
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Nome #
Self-assembling Releasable Thiocolchicine–Diphenylbutenylaniline Conjugates 394
Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis 389
The effects of combinatorial chemistry and technologies on drug discovery and biotechnology : A mini review 351
Stimulus-responsive liposomes for biomedical applications 324
Smac127 Has Proapoptotic and Anti-Inflammatory Effects on Rheumatoid Arthritis Fibroblast-Like Synoviocytes 263
Synthesis and biological evaluation of dual action cyclo-RGD/SMAC mimetic conjugates targeting αvβ3/αvβ5 integrins and IAP proteins 262
Regulation of HuR structure and function by dihydrotanshinone-I 219
Nanolipid-trehalose conjugates and nano-assemblies as putative autophagy inducers 219
New SMAC mimetic compounds as apoptosis inducers 218
Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo[5.3.0]alkane smac mimetics. Structure, activity, and recognition principles 205
Identification of Isoform 2 Acid-Sensing Ion Channel Inhibitors as Tool Compounds for Target Validation Studies in CNS 194
Structural Basis for Bivalent Smac-Mimetics Recognition in the IAP Protein Family 189
In vitro effect of second mitochondria-derived activator of caspases (SMAC) mimic compounds on myeloid leukemia cell lines 181
Design of SMAC-Diablo Mimics Targeting XIAP/BIR3 Domain for Apoptosis Induction: a Computational Study. 180
Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent Smac-mimetic 180
Smac mimetics induce inflammation and necrotic tumour cell death by modulating macrophage activity 179
Proapoptotic Activity of a Monomeric Smac Mimetic on Human Fibroblast-Like Synoviocytes from Patients with Rheumatoid Arthritis 172
Effect of Second Mitochondria-Derived Activator of Caspases (Smac) Mimetic Compounds on Leukemic Cell Lines 164
Second mitochondria-derived activator of caspases mimetic compounds (Smac) enhance tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) pro-Apoptotic effect on human myeloid leukemia cell lines 160
A NMR STUDY OF SMAC MIMICS TARGETING BOTH THE BIR2 AND BIR3 DOMAINS IN XIAP PROTEIN. 159
HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis 156
Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function 152
New homo- and heretodimeric SMAC mimetic compound as apoptosis inducers 151
Dimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part II : Structural and biological characterization 149
Single-agent Smac-mimetic compounds induce apoptosis in B chronic lymphocytic leukaemia (B-CLL) 147
PRO-APOPTOTIC EFFECT OF A NEW SMAC-MIMETIC ON B-CLL CELLS IN VITRO 145
Structure-based design and molecular profiling of Smac-mimetics selective for cellular IAPs 144
Novel second mitochondria-derived activator of caspases (Smac) mimetic compounds sensitize human leukemic cell lines to conventional chemotherapeutic drug-induced and death receptor-mediated apoptosis 139
Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib 138
Synergistic in vitro effect of Second Mitochondria-derived Activator of Caspases mimetic compounds (Smac) and Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) on human acute leukemia cell lines 136
Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy 136
Synthesis of non glycosidic nucleobase-sugar mimetics 136
Combinatorial chemistry and natural products. Teicoplanin aglycon as a molecular scaffold for solid phase synthesis of combinatorial libraries 133
Detecting drugs in dry bone: a pilot study of skeletal remains with a post-mortem interval over 23 years 133
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2 131
Antitumor activity of a novel homodimeric SMAC mimetic in ovarian carcinoma 131
Oncogenic KRAS sensitizes premalignant, but not malignant cells, to Noxa-dependent apoptosis through the activation of the MEK/ERK pathway 131
Counteracting Pseudomonas aeruginosa biofilm formation by inhibition of novel targets : regulation of the levels of the di-cyclic-GMP signal molecule 129
Preparation of 56-O-alkyl derivatives of aglycones and pseudoaglycones of teicoplanin as antibacterials 127
A NMR and computational study of Smac mimics targeting both the BIR2 and BIR3 domains in XIAP protein 126
An inhibitor of tau hyperphosphorylation prevents severe motor impairments in tau transgenic mice 125
Recognition of Smac-mimetic compounds by the BIR domain of cIAP1 125
Preparation of new substituted alkylamide derivatives of teicoplanin as antibacterials 125
Copper(II) in organic synthesis. IV. Reaction of the copper(II) acetate complex of isatin-3-arylhydrazones with dimethyl acetylenedicarboxylate 124
4-Connected azabicyclo[5.3.0]decane Smac mimetics-Zn2+ chelators as dual action antitumoral agents 123
New SMAC-Mimetic Compounds Strongly Induce In Vitro Apoptosis of Human Lymphocytes From Patients with Chronic Lymphocytic Leukemia 123
Preparation of basic prolineamide derivatives of GE2270 and GE2270-like antibiotics 121
Synthesis of dual action Smac/Zinc-Chelator conjugates as putative proapoptotic agents 119
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors 119
Intracisternal delivery of PEG-coated gold nanoparticles results in high brain penetrance and long-lasting stability 118
Synthesis and in vitro study of novel neuraminidase inhibitors against avian influenza virus 117
Homo- and heterodimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part I : synthesis 114
SPION-Smac mimetic nano-conjugates: putative pro-apoptotic agents in oncology 114
Preparation of indolylpropenylideneheterocycles for treatment of osteoporosis 114
Copper(II) in organic synthesis. II. A stereocontrolled route to alkylprolines 113
Allylic functionalization of 2,5- and 2,4-cyclohexadiene-1,3-dicarboxylates 112
(4S)-p-Hydroxybenzyl-1,3-oxazolidin-2-one as a solid-supported chiral auxiliary in asymmetric 1,3-dipolar cycloadditions 111
Chimica combinatoriale 111
Combinatorial chemistry and natural products: Determination of the biological activity of on-bead, double cleavable teicoplanin aglycone (TD) 110
Solution Synthesis of Two Orthogonally Protected Lactosides as Tetravalent Disaccharide-Based Scaffolds 108
CHI's Fourth Annual Drug Discovery Chemistry Conference. Kinase inhibitor chemistry: charting the chemical space. 7-8 April 2009, San Diego, CA, USA 108
Preparation of 5-(indol-2-yl)-2,4-pentadienoates as inhibitors of bone resorption. 108
Trialkylsilyl cyanide, polymer-supported 106
A combinatorial approach to [1,5]benzothiazepine derivatives as potential antibacterial agents 104
Peptide aldehydes as inhibitors of HIV protease 102
DFG-in and DFG-out homology models of TrkB kinase receptor: Induced-fit and ensemble docking 99
Application of combinatorial technologies for catalyst design and development 99
Transport of the antibacterial agent oxazolidin-2-one and derivatives across intestinal (Caco-2) and renal (MDCK) epithelial cell lines 98
Preparation of N,N-bridged, nitrogen-substituted carbacyclic indolocarbazoles for use in pharmaceutical compositions as protein kinase inhibitors 98
Regiospecific synthesis of mono-N-substituted indolopyrrolocarbazoles 97
Dual action Smac mimetics-zinc chelators as pro-apoptotic antitumoral agents 95
Introduction to combinatorial chemistry and technologies : principles and methods 94
Immobilized benzylpenicillin acylase : application to the synthesis of optically active forms of carnitine and propranolol 94
Overview of Combinatorial Technologies in Modern Natural Products Research 93
Synthesis of polymer-bound Fischer chromium alkoxy and aminocarbene complexes 93
HuR-targeted agents: An insight into medicinal chemistry, biophysical, computational studies and pharmacological effects on cancer models 92
Combinatorial chemistry: basic principles and new trends 92
Chemical modulators of protein misfolding and neurodegenerative disease 92
Further information on the steric course on the bakers' yeast reduction of 4-substituted-3-oxobutanoates 91
Combination of Smac-mimetics and TNFalpha induce apoptosis in glioma cell lines 91
Stereoselective alkenylation of aldehydes with phosphorus carbanions : preparation of E- and Z-2-alkoxy- and 2-aryloxy-2-alkenoates 90
Synthesis and biological activity of O56-substituted carboxyesters and carboxamides of teicoplanin aglycone 90
Synthesis and antimicrobial activity of oxazolidinones and related heterocycles 90
Preparation of basic oxazolineamide derivatives of GE2270 and GE2270-like antibiotics 90
Chemical diversity as a driving force to design and put in practice synthetic strategies leading to combinatorial libraries for lead discovery and lead optimization 89
Synthesis of 2,5- and 2,4-cyclohexadiene-1,3-dicarboxylates via reductive alkylation of isophthalates 89
Preparation of N-carbacycle monosubstituted indolocarbazoles for therapeutic use as protein kinase inhibitors 87
Combinatorial Chemistry 87
Studies on the novel anti-staphyloccal compound nematophin 86
A new analytical method for anchoring quantification of amines on resin support 84
Stereoselective synthesis of conformationally constrained cyclohexanediols: a set of molecular scaffolds for the synthesis of glycomimetics 84
Combinatorial chemistry and high-throughput screening in drug discovery: different strategies and formats 82
Synthesis of mono- and disubstituted 1H-imidazo [1,2-b] pyrazoles 81
SPION-Smac mimetic nanoconjugates : putative pro-apoptotic agents in oncology 80
Synergy between chemistry, genomics, and proteomics 78
Polymer-supported haloarene chromium dicarbonyl isonitrile complexes: a study of their synthesis and reactivity 76
New polymer-bound haloarene chromium dicarbonyl isocyanide complexes: a successful study validating their use in chemistry 76
Stabilization of the retromer complex: analysis of novel binding sites of bis-1,3-phenyl guanylhydrazone 2a to the VPS29/VPS35 interface 75
Dual Functionalized Liposomes for Selective Delivery of Poorly Soluble Drugs to Inflamed Brain Regions 75
High throughput purification methods in combinatorial solution phase synthesis 75
Totale 13.328
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Categoria #
all - tutte 48.306
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 48.306
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202093 0 0 0 0 0 0 0 0 0 0 57 36
2020/20211.505 75 113 108 57 158 87 113 89 132 118 352 103
2021/20221.822 135 83 70 97 213 130 132 126 144 183 191 318
2022/20231.938 314 186 173 224 159 371 52 120 173 34 90 42
2023/20241.413 44 80 67 46 250 103 90 110 46 140 188 249
2024/20252.390 129 297 92 284 209 124 225 367 261 293 109 0
Totale 16.213