DI LASCIO, SIMONA
DI LASCIO, SIMONA
Dipartimento di Biotecnologie Mediche e Medicina Traslazionale
Evidence of a dual mechanism of action underlying the anti-proliferative and cytotoxic effects of ammonium-alkyloxy-stilbene-based α7- and α9- nicotinic ligands on glioblastoma cells
2022 S. Pucci, C. Bolchi, F. Bavo, M. Pallavicini, C. De Palma, M. Renzi, S. Fucile, R. Benfante, S. Di Lascio, D. Lattuada, J. Bessereau, M. D'Alessandro, V. Risson, M. Zoli, F. Clementi, C. Gotti
Generation of two hiPSC lines (UMILi027-A and UMILi028-A) from early and late-onset Congenital Central hypoventilation Syndrome (CCHS) patients carrying a polyalanine expansion mutation in the PHOX2B gene
2022 A.L. Cuadros Gamboa, R. Benfante, M. Nizzardo, T. Bachetti, P. Pelucchi, V. Melzi, C. Arzilli, M. Peruzzi, R.A. Reinbold, S. Cardani, A. Morrone, R. Guerrini, I. Zucchi, S. Corti, I. Ceccherini, R. Piumelli, N. Nassi, S. Di Lascio, D. Fornasari
Research Advances on Therapeutic Approaches to Congenital Central Hypoventilation Syndrome (CCHS)
2021 S. Di Lascio, R. Benfante, S. Cardani, D. Fornasari
Acetyl-L-carnitine in chronic pain: A narrative review
2021 P. Sarzi-Puttini, V. Giorgi, S. Di Lascio, D. Fornasari
Choline and nicotine increase glioblastoma cell proliferation by binding and activating α7- and α9- containing nicotinic receptors
2021 S. Pucci, F. Fasoli, M. Moretti, R. Benfante, S. Di Lascio, P. Viani, A. Daga, T.J. Gordon, M. Mcintosh, M. Zoli, F. Clementi, C. Gotti
Acetylcholinesterase inhibitors targeting the cholinergic anti-inflammatory pathway : a new therapeutic perspective in aging-related disorders
2019 R. Benfante, S. Di Lascio, S. Cardani, D. Fornasari
Molecular insights into the role of the polyalanine region in mediating PHOX2B aggregation
2019 L. Pirone, L. Caldinelli, S. Di Lascio, R. Di Girolamo, S. Di Gaetano, D. Fornasari, L. Pollegioni, R. Benfante, E. Pedone
Effect of donepezil on the expression and responsiveness to LPS of CHRNA7 and CHRFAM7A in macrophages : a possible link to the cholinergic anti-inflammatory pathway
2019 A. Maroli, S. Di Lascio, L. Drufuca, S. Cardani, E. Setten, M. Locati, D. Fornasari, R. Benfante
alpha9- and alpha7-containing receptors mediate the pro-proliferative effects of nicotine in the A549 adenocarcinoma cell line
2018 V. Mucchietto, F.M. Fasoli, P. Susanna, M. Moretti, B. Roberta, A. Maroli, S. DI LASCIO, C. Bolchi, M. Pallavicini, D. Cheryl, M. Michael, F. Clementi, G. Cecilia
Structural and functional differences in PHOX2B frameshift mutations underlie isolated or syndromic congenital central hypoventilation syndrome
2018 S. DI LASCIO, B. Roberta, D.Z. Eleonora, S. Cardani, A. Annalisa, D.M.M. Fornasari, C. Isabella, B. Tiziana
Desogestrel down-regulates PHOX2B and its target genes in progesterone responsive neuroblastoma cells
2018 S. Cardani, S. Di Lascio, D. Belperio, E. Di Biase, I. Ceccherini, R. Benfante, D. Fornasari
Advances in the molecular biology and pathogenesis of congenital central hypoventilation syndrome—implications for new therapeutic targets
2018 S. Di Lascio, R. Benfante, S. Cardani, D. Fornasari
Alanine expansions associated with congenital central hypoventilation syndrome impair PHOX2B homeodomain-mediated dimerization and nuclear import
2016 S. Di Lascio, D. Belperio, R. Benfante, D. Fornasari
Design and characterization of superpotent bivalent ligands targeting oxytocin receptor dimers via a channel-like structure
2016 M. Busnelli, G. Kleinau, M. Muttenthaler, S. Stoev, M. Manning, L. Bibic, L.A. Howell, P.J. Mccormick, S. DI LASCIO, D. Braida, M. Sala, G.E. Rovati, T.G. Bellini, B. Chini
PHOX2A and PHOX2B are differentially regulated during retinoic acid-driven differentiation of SK-N-BE(2)C neuroblastoma cell line
2016 S. Di Lascio, E. Saba, D. Belperio, A. Raimondi, H. Lucchetti, D. Fornasari, R. Benfante
Transcriptional dysregulation and impairment of PHOX2B auto-regulatory mechanism in the pathogenesis of Congenital Central Hypoventilation Syndrome
2014 S. Di Lascio, S. Moncini, T. Bachetti, I. Ceccherini, R. Benfante, D. Fornasari
The structure and functions of the transcription factor PHOX2B : new insights in the molecular pathogenesis of congenital central hypoventilation syndrome
2014 D. Belperio, S. Di Lascio, R. Benfante, D. Fornasari
Transcriptional dysregulation and impairment of PHOX2B auto-regulatory mechanism induced by polyalanine expansion mutations associated with congenital central hypoventilation syndrome
2013 S. Di Lascio, T. Bachetti, E. Saba, I. Ceccherini, R. Benfante, D. Fornasari
Identification and characterization of regulatory elements in the promoter of ACVR1, the gene mutated in Fibrodysplasia Ossificans Progressiva
2013 F. Giacopelli, S. Cappato, L. Tonachini, M. Mura, S. Di Lascio, D. Fornasari, R. Ravazzolo, R. Bocciardi
The E3 ubiquitin ligase TRIM11 mediates the degradation of congenital central hypoventilation syndrome-associated polyalanine-expanded PHOX2B
2012 S. Parodi, E. Di Zanni, S. Di Lascio, P. Bocca, I. Prigione, D. Fornasari, M. Pennuto, T. Bachetti, I. Ceccherini