DI FRANCESCO, DARIO
DI FRANCESCO, DARIO
Dipartimento di Bioscienze
Chinese natural compound decreases pacemaking of rabbit cardiac sinoatrial cells by targeting second messenger regulation of f-channels
2022 C. Piantoni, M. Paina, D. Molla, S. Liu, G. Bertoli, H. Jiang, Y. Wang, Y. Wang, Y. Wang, D. Difrancesco, A. Barbuti, A. Bucchi, M. Baruscotti
Gating movements and ion permeation in {HCN}4 pacemaker channels
2021 A.C. Saponaro, D. Bauer, M. Hunter Giese, P. Swuec, A. Porro, F. Gasparri, A. Sadat Sharifzadeh, A. CHAVES SANJUAN, L. Alberio, G. Parisi, G. Cerutti, O.B. Clarke, K. Hamacher, H.M. Colecraft, F. Mancia, W.A. Hendrickson, S.A. Siegelbaum, D. DI FRANCESCO, M. Bolognesi, G. Thiel, B. Santoro, A. Moroni
A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate
2021 A. D'Souza, Y. Wang, C. Anderson, A. Bucchi, M. Baruscotti, S. Olieslagers, P. Mesirca, A.B. Johnsen, S. Mastitskaya, H. Ni, Y. Zhang, N.B. BmBCh, C. Cox, S. Wegner, B. Bano-Otalora, C. Petit, E. Gill, S.J. Logantha, H. Dobrzynski, N. Ashton, G. Hart, R. Zhang, H. Zhang, E.J. Cartwright, U. Wisloff, M.E. Mangoni, P. Da Costa Martins, H.D. Piggins, D. DiFrancesco, M.R. Boyett
Functional Characterization of a Novel Scn5a Mutation Associated With the Brugada Syndrome
2019 A. Frosio, D. Molla, G. Bertoli, C. Bazzini, R. Milanesi, F. Gennaro, A.F. Barbuti, A. Bucchi, L. Moretti, P. Marchese, D. DI FRANCESCO, M. Baruscotti
A Loss-of-Function HCN4 Mutation Associated With Familial Benign Myoclonic Epilepsy in Infancy Causes Increased Neuronal Excitability
2018 G. Campostrini, J.C. Difrancesco, B. Castellotti, R. Milanesi, T. Gnecchi-Ruscone, M. Bonzanni, A. Bucchi, M. Baruscotti, C. Ferrarese, S. Franceschetti, L. Canafoglia, F. Ragona, E. Freri, A. Labate, A. Gambardella, C. Costa, C. Gellera, T. Granata, A. Barbuti, D. Di Francesco
Preferential myofibroblast differentiation of cardiac mesenchymal progenitor cells in the presence of atrial fibrillation
2018 E. Gambini, G.L. Perrucci, B. Beatrice, G. Spaltro, G. Campostrini, M.C. Lionetti, A. Pilozzi, F. Martinelli, F. Andrea, D. Difrancesco, A. Barbuti, G. Pompilio
A novel de novo HCN1 loss-of-function mutation in genetic generalized epilepsy causing increased neuronal excitability
2018 M. Bonzanni, J.C. Difrancesco, R. Milanesi, G. Campostrini, B. Castellotti, A. Bucchi, M. Baruscotti, C. Ferrarese, S. Franceschetti, L. Canafoglia, F. Ragona, E. Freri, A. Labate, A. Gambardella, C. Costa, I. Rivolta, C. Gellera, T. Granata, A. Barbuti, D. Di Francesco
Generation of human induced pluripotent stem cells (EURACi001-A, EURACi002-A, EURACi003-A) from peripheral blood mononuclear cells of three patients carrying mutations in the CAV3 gene
2018 M. Viviana, P. Benzoni, S. Landi, C. Murano, M. Langione, B.M. Motta, B. Serena, R. Silipigni, D.S. Marina, P. Peter P., D. Difrancesco, G. Elisabetta, A. Barbuti, R. Alessandra
A gain-of-function mutation in the cardiac pacemaker HCN4 channel increasing cAMP sensitivity is associated with familial Inappropriate Sinus Tachycardia
2017 M. Baruscotti, A. Bucchi, R. Milanesi, M. Paina, A. Barbuti, T. Gnecchi Ruscone, E. Bianco, L. Vitali Serdoz, R. Cappato, D. Difrancesco
Mammalian γ2 AMPK regulates intrinsic heart rate
2017 Y. Arash, B. Mohamed, A. Bucchi, S. Syevda, P. Katalin, H. Neil, J. Julia J, T. Kirill V, S. Emily J, W. Markus, C. Gabor, S. Violetta, G. Sahar, N. Chinh, S. Alexander, C. Joshua R. St, R. Christian, O. Yosuke, Y. Dongmei, W. Mingyi, Z. Bruce D, M. Jack M, R. Daniel R, R. Christopher, M. Paina, L. Joonho, Z. Jing, A. Ismayil, M. Michael G, T. Yelena S, B. Dilair, S. Natasha, L. Helen, P. Rathi, D.B. Joseph, S. Owen M, G. John, M. Hannah, M. Mahon L, B. Youlia, K. Matthew, D.S. Pedro P. N, B. Nicola J, W. Angela, G. Katja, I. Henrik, D. Gillian, F. David J. P, S. Jürgen E, T. Andrew, W. Olaf, C. Keith M, C. Richard J, S. Eduardo B, P. David J, R. Charles S, C. David, P. Catherine, D. Robert, M. Baruscotti, D. DI FRANCESCO, L. Edward G, W. Hugh, A. Houman
The expression of the rare caveolin-3 variant T78M alters cardiac ion channels function and membrane excitability
2017 G. Campostrini, M. Bonzanni, A. Lissoni, C. Bazzini, R. Milanesi, E. Vezzoli, M. Francolini, M. Baruscotti, A. Bucchi, I. Rivolta, M. Fantini, S. Severi, R. Cappato, L. Crotti, P.J. Schwartz, D. Di Francesco, A. Barbuti
Current understanding of the pathophysiological mechanisms responsible for inappropriate sinus tachycardia : role of the If “funny” current
2016 M. Baruscotti, E. Bianco, A. Bucchi, D. Difrancesco
Mutation in S6 domain of HCN4 channel in patient with suspected Brugada syndrome modifies channel function
2016 S. Biel, M. Aquila, B. Hertel, A. Berthold, T. Neumann, D. Difrancesco, A. Moroni, G. Thiel, S. Kauferstein
Rate-adapted dynamic-clamp of the funny current in sinoatrial pacemaker cells
2016 C. Bartolucci, E. Ravagli, A. Bucchi, M. Baruscotti, D. Difrancesco, S. Severi
Anacardic acid and thyroid hormone enhance cardiomyocytes production from undifferentiated mouse ES cells along functionally distinct pathways
2016 A. Re, S. Nanni, A. Aiello, S. Granata, C. Colussi, G. Campostrini, F. Spallotta, S. Mattiussi, V. Pantisano, C. D’Angelo, A. Biroccio, A. Rossini, A. Barbuti, D. Difrancesco, F. Trimarchi, A. Pontecorvi, C. Gaetano, A. Farsetti
Cell-specific dynamic clamp analysis of the role of funny If current in cardiac pacemaking
2016 E. Ravagli, A. Bucchi, C. Bartolucci, M. Paina, M. Baruscotti, D. Difrancesco, S. Severi
Higher cardiogenic potential of iPSCs derived from cardiac versus skin stromal cells
2016 V. Meraviglia, J. Wen, L. Piacentini, G. Campostrini, C. Wang, M. Florio, V. Azzimato, L. Fassina, M. Langes, J. Wong, M. Miragoli, C. Gaetano, G. Pompilio, A. Barbuti, D. Difrancesco, D. Mascalzoni, P. Pramstaller, G. Colombo, H. Chen, A. Rossini
Dysfunctional HCN ion channels in neurological diseases
2015 J.C. Difrancesco, D. Difrancesco
HCN4, Sinus Bradycardia and Atrial Fibrillation
2015 D. Di Francesco
Exercise training reduces resting heart rate via downregulation of the funny channel HCN4
2014 A. D'Souza, A. Bucchi, A.B. Johnsen, S.J.R.J. Logantha, O. Monfredi, J. Yanni, S. Prehar, G. Hart, E. Cartwright, U. Wisloff, H. Dobryznski, D. Difrancesco, G.M. Morris, M.R. Boyett