| Nome |
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition), file dfa8b994-5f94-748b-e053-3a05fe0a3a96
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4962
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Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer, file dfa8b98e-5b1f-748b-e053-3a05fe0a3a96
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4646
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Blood orange juice inhibits fat accumulation in mice, file dfa8b98f-b24d-748b-e053-3a05fe0a3a96
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1031
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A dual role for Hdac1 : oncosuppressor in tumorigenesis, oncogene in tumor maintenance, file dfa8b990-9496-748b-e053-3a05fe0a3a96
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1001
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New method to detect histone acetylation levels by flow cytometry, file dfa8b98e-4738-748b-e053-3a05fe0a3a96
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986
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Entinostat for the treatment of breast cancer, file dfa8b99f-34e8-748b-e053-3a05fe0a3a96
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687
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Modulation of pro- and anti-apoptotic factors in human melanoma cells exposed to histone deacetylase inhibitors, file dfa8b98f-b74b-748b-e053-3a05fe0a3a96
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357
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Mechanisms of selective anticancer action of histone deacetylase inhibitors, file dfa8b98e-4870-748b-e053-3a05fe0a3a96
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349
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Differentiation response of acute promyelocytic leukemia cells and PML/RAR alpha leukemogenic activity studies by real-time RT-PCR, file dfa8b98e-4818-748b-e053-3a05fe0a3a96
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304
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Immunohistochemical detection of Ym1/Ym2 chitinase-like lectins associated with hyalinosis and polypoid adenomas of the transitional epithelium in a mouse with acute myeloid leukemia, file dfa8b98e-5c91-748b-e053-3a05fe0a3a96
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284
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Beclin 1 restrains tumorigenesis through Mcl-1 destabilization in an autophagy-independent reciprocal manner, file dfa8b996-0619-748b-e053-3a05fe0a3a96
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268
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Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis, file dfa8b999-905b-748b-e053-3a05fe0a3a96
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267
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Modulation of pro- and anti-apoptotic factors in human melanoma cells exposed to histone deacetylase inhibitors, file dfa8b98f-b74c-748b-e053-3a05fe0a3a96
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260
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Fasting-Mimicking Diet Is Safe and Reshapes Metabolism and Antitumor Immunity in Patients with Cancer, file 226480f2-8d43-46fb-933e-6f6798bdaa81
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211
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Phosphorylation of SOS1 on tyrosine 1196 promotes its RAC GEF activity and contributes to BCR-ABL leukemogenesis, file dfa8b99a-4f75-748b-e053-3a05fe0a3a96
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188
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Pathology Tissue-quantitative Mass Spectrometry Analysis to Profile Histone Post-translational Modification Patterns in Patient Samples, file dfa8b996-0da2-748b-e053-3a05fe0a3a96
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177
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PML-RAR induces promyelocytic leukemias with high efficiency following retroviral gene transfer into purified murine hematopoietic progenitors, file dfa8b990-5f99-748b-e053-3a05fe0a3a96
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152
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PAT-ChIP coupled with laser microdissection allows the study of chromatin in selected cell populations from paraffin-embedded patient samples, file dfa8b991-91f2-748b-e053-3a05fe0a3a96
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147
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Leukemia-associated fusion proteins : multiple mechanisms of action to drive cell transformation, file dfa8b98e-475b-748b-e053-3a05fe0a3a96
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117
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Mass-spectrometry analysis of histone post-translational modifications in pathology tissue using the PAT-H-MS approach, file dfa8b995-c51b-748b-e053-3a05fe0a3a96
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105
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Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis, file dfa8b99f-5114-748b-e053-3a05fe0a3a96
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103
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Synthetic Lethality Triggered by Combining Olaparib with BRCA2-Rad51 Disruptors, file dfa8b9a5-8898-748b-e053-3a05fe0a3a96
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99
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The methyl-CpG binding protein MBD1 is required for PML-RARα function, file dfa8b990-e584-748b-e053-3a05fe0a3a96
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83
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Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation, file dfa8b9a5-3e3f-748b-e053-3a05fe0a3a96
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78
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MicroRNA-222 Regulates Melanoma Plasticity, file dfa8b9a2-fbf5-748b-e053-3a05fe0a3a96
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71
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LSD1-directed therapy affects glioblastoma tumorigenicity by deregulating the protective ATF4-dependent integrated stress response, file c7190422-a954-4f7d-9193-0ed04301ff76
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64
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Extensive and systematic rewiring of histone post-translational modifications in cancer model systems, file dfa8b9a9-81d1-748b-e053-3a05fe0a3a96
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40
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Chromatin immunoprecipitation and high-throughput sequencing from paraffin-embedded pathology tissue, file dfa8b990-832c-748b-e053-3a05fe0a3a96
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38
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PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response, file dfa8b99a-84aa-748b-e053-3a05fe0a3a96
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32
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The self-association coiled-coil domain of PML is sufficient for the oncogenic conversion of the retinoic acid receptor (RAR) alpha, file dfa8b990-8333-748b-e053-3a05fe0a3a96
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21
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Single cell-derived spheroids capture the self-renewing subpopulations of metastatic ovarian cancer, file dfa8b9a9-8591-748b-e053-3a05fe0a3a96
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17
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Pharmacological inhibition of {LSD}1 triggers myeloid differentiation by targeting {GSE}1, a novel oncogene in {AML}, file 285d3d29-1f22-4539-aa5f-9d765f41ab9a
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10
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Guidelines for the use and interpretation of assays for monitoring autophagy, file dfa8b98f-e1d0-748b-e053-3a05fe0a3a96
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9
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HDACs link the DNA damage response, processing of double-strand breaks and autophagy, file dfa8b991-1ff4-748b-e053-3a05fe0a3a96
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8
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The DNA demethylating agent decitabine activates the TRAIL pathway and induces apoptosis in acute myeloid leukemia, file dfa8b990-82ac-748b-e053-3a05fe0a3a96
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7
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Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer, file dfa8b998-9823-748b-e053-3a05fe0a3a96
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7
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Pharmacological inhibition of LSD1 triggers myeloid differentiation by targeting GSE1 oncogenic functions in AML, file dfa8b9a9-bb6c-748b-e053-3a05fe0a3a96
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7
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CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one- carbon metabolism in breast cancer, file 7b7526c6-a01b-425f-8a28-bf22e74a7460
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6
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Semantic and geographical analysis of COVID-19 trials reveals a fragmented clinical research landscape likely to impair informativeness, file fe787370-c462-4a90-9b4e-021f87b24f88
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6
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Functional characterization of a novel FGFR1OP-RET rearrangement in hematopoietic malignancies, file dfa8b990-f2a0-748b-e053-3a05fe0a3a96
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5
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Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer, file dfa8b997-47f4-748b-e053-3a05fe0a3a96
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5
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Quantitative chemical proteomics identifies novel targets of the anti-cancer multi-kinase inhibitor E-3810, file a85f3f52-f115-4672-bed7-6c5f34f4cf97
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4
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Cinnamic anilides as new mitochondrial permeability transition pore inhibitors endowed with ischemia-reperfusion injury protective effect in vivo, file dfa8b991-3949-748b-e053-3a05fe0a3a96
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4
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Valproic acid induces differentiation and transient tumor regression, but spares leukemia-initiating activity in mouse models of APL, file dfa8b990-78c7-748b-e053-3a05fe0a3a96
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3
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Molecular pathways: old drugs define new pathways: non-histone acetylation at the crossroads of the DNA damage response and autophagy, file dfa8b990-7d94-748b-e053-3a05fe0a3a96
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3
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Chromatin accessibility, p300 and histone acetylation define PML-RARα and AML1-ETO binding sites in acute myeloid leukemia, file dfa8b990-8006-748b-e053-3a05fe0a3a96
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3
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In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype, file dfa8b996-3888-748b-e053-3a05fe0a3a96
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3
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Dual modulation of MCL-1 and mTOR determines the response to sunitinib, file dfa8b997-c898-748b-e053-3a05fe0a3a96
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3
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Sex-based dimorphism of anticancer immune response and molecular mechanisms of immune evasion, file dfa8b9a8-2700-748b-e053-3a05fe0a3a96
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3
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Erratum: PML is required for telomere stability in non-neoplastic human cells (vol 35, pg 1811, 2016), file dfa8b995-aacd-748b-e053-3a05fe0a3a96
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2
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In vitro and in vivo hematopoietic potential of human stem cells residing in muscle tissue, file dfa8b996-a1fc-748b-e053-3a05fe0a3a96
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2
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Preclinical models of breast cancer: Two-way shuttles for immune checkpoint inhibitors from and to patient bedside, file dfa8b9a5-fa29-748b-e053-3a05fe0a3a96
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2
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Anticancer innovative therapy congress: Highlights from the 10th anniversary edition, file dfa8b9a9-cca2-748b-e053-3a05fe0a3a96
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2
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CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one- carbon metabolism in breast cancer, file dfa8b9aa-5993-748b-e053-3a05fe0a3a96
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2
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Long non-coding RNA TINCR suppresses metastatic melanoma dissemination by preventing ATF4 translation, file 18bc8980-61ff-43d1-aff8-b991972eeb02
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1
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Sex and cancer immunotherapy: Current understanding and challenges, file 705d31ed-c5b1-4c83-95bc-7476aad2be2b
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1
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Molecular and biological analysis of histone deacetylase inhibitors with diverse specificities, file dfa8b991-e238-748b-e053-3a05fe0a3a96
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1
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Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer, file dfa8b992-7cc7-748b-e053-3a05fe0a3a96
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1
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PML is required for telomere stability in non-neoplastic human cells, file dfa8b992-dab3-748b-e053-3a05fe0a3a96
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1
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The International Human Epigenome Consortium : A Blueprint for Scientific Collaboration and Discovery, file dfa8b997-4fa8-748b-e053-3a05fe0a3a96
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1
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Self-renewal of tumor cells : Epigenetic determinants of the cancer stem cell phenotype, file dfa8b998-0d48-748b-e053-3a05fe0a3a96
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1
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Endosomal trafficking and DNA damage checkpoint kinases dictate survival to replication stress by regulating amino acid uptake and protein synthesis, file dfa8b9a8-8d60-748b-e053-3a05fe0a3a96
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1
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Co-targeting leukemia-initiating cells and leukemia bulk leads to disease eradication, file dfa8b9a9-f833-748b-e053-3a05fe0a3a96
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1
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| Totale |
17260 |