CIGNARELLA, GIORGIO
 Distribuzione geografica
Continente #
EU - Europa 3.698
AS - Asia 3.007
NA - Nord America 2.839
SA - Sud America 241
AF - Africa 53
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 1
Totale 9.843
Nazione #
US - Stati Uniti d'America 2.755
GB - Regno Unito 1.603
CN - Cina 973
SG - Singapore 908
RU - Federazione Russa 412
SE - Svezia 409
DE - Germania 313
IT - Italia 290
TR - Turchia 273
HK - Hong Kong 266
VN - Vietnam 187
BR - Brasile 181
KR - Corea 163
FR - Francia 148
IE - Irlanda 130
UA - Ucraina 122
NL - Olanda 103
IN - India 88
FI - Finlandia 84
EU - Europa 76
CA - Canada 46
BD - Bangladesh 29
JP - Giappone 27
ID - Indonesia 23
CO - Colombia 22
CI - Costa d'Avorio 21
MX - Messico 20
GR - Grecia 19
BE - Belgio 16
AR - Argentina 14
PH - Filippine 14
IQ - Iraq 13
UZ - Uzbekistan 10
DK - Danimarca 8
EC - Ecuador 8
ES - Italia 8
ZA - Sudafrica 8
PK - Pakistan 7
MA - Marocco 6
MY - Malesia 6
JM - Giamaica 5
KE - Kenya 5
PY - Paraguay 5
SA - Arabia Saudita 5
VE - Venezuela 5
AT - Austria 4
JO - Giordania 4
CL - Cile 3
CZ - Repubblica Ceca 3
EG - Egitto 3
LV - Lettonia 3
NO - Norvegia 3
PL - Polonia 3
TN - Tunisia 3
AU - Australia 2
BY - Bielorussia 2
CH - Svizzera 2
ET - Etiopia 2
GT - Guatemala 2
HN - Honduras 2
HU - Ungheria 2
NP - Nepal 2
PT - Portogallo 2
RO - Romania 2
TH - Thailandia 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
AG - Antigua e Barbuda 1
AL - Albania 1
AM - Armenia 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BJ - Benin 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EE - Estonia 1
GL - Groenlandia 1
IM - Isola di Man 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
MD - Moldavia 1
ME - Montenegro 1
NG - Nigeria 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
PA - Panama 1
PE - Perù 1
PF - Polinesia Francese 1
PR - Porto Rico 1
SI - Slovenia 1
SN - Senegal 1
SV - El Salvador 1
TL - Timor Orientale 1
TT - Trinidad e Tobago 1
ZW - Zimbabwe 1
Totale 9.919
Città #
Southend 1.536
Singapore 465
Santa Clara 272
Hong Kong 251
Chandler 246
Seattle 210
Beijing 207
San Jose 171
Princeton 168
Ashburn 160
Dublin 130
Wilmington 124
Ann Arbor 101
Milan 95
Council Bluffs 91
Mountain View 85
Redmond 85
Dallas 82
Sakarya 74
Lauterbourg 69
Nanjing 67
Des Moines 63
Los Angeles 61
Ho Chi Minh City 59
Bengaluru 53
Jacksonville 51
Dearborn 48
Moscow 48
Buffalo 46
Guangzhou 45
Boardman 42
Hanoi 38
Shanghai 35
Woodbridge 35
Hefei 34
Shenyang 33
Fairfield 31
Tianjin 31
Hangzhou 28
Serra 28
Grafing 25
Kent 25
Jinan 23
Ottawa 23
Tokyo 23
Abidjan 21
Andover 20
Shenzhen 20
Somerville 20
Athens 19
Cangzhou 19
Columbus 19
Nanchang 19
Bogotá 18
Changsha 18
Fuzhou 17
Houston 17
The Dalles 17
Wuhan 17
Eitensheim 16
São Paulo 16
Venezia 16
Zhengzhou 16
Brussels 15
Hebei 15
Jiaxing 14
Istanbul 13
Seoul 13
Frankfurt am Main 12
Kiez 12
New York 12
Nürnberg 12
Düsseldorf 11
Mexico City 11
Haiphong 10
Dongguan 9
Helsinki 9
Munich 9
Ningbo 9
Toronto 9
Turin 9
Xiamen 9
Dong Ket 8
Kwai Chung 8
Redwood City 8
Da Nang 7
Medford 7
Taizhou 7
Cambridge 6
Chicago 6
Jakarta 6
Nuremberg 6
Rome 6
San Diego 6
Tashkent 6
Auburn Hills 5
Bitonto 5
Biên Hòa 5
Brasília 5
Goiânia 5
Totale 6.267
Nome #
Behaviour of 5,6-dihydrothieno[2,3-h]cinnolin-3(2H)-one and 5,6-dihydrothieno[3,2-h]cinnolin-3(2H)-one towards hydrazine. Synthesis of thienocinnolinones and of 4-aminothienocinnolinones 244
Synthesis and biological activity of new antiviral compounds 230
Pharmacokinetics and distribution of sodium 3,4-diaminonaphtalene-1-sulfonate, a Congo Red derivative active in inhibiting PrPres replication 229
Synthesis and cytotoxic activities of 3-(5-phenyl-[1,3,4]oxadiazol-2-yl)-1H-benzo[g]indole and related compounds 225
Synthesis, Modelling, and Antimitotic Properties of Tricyclic Systems Characterised by a 2-(5-Phenyl-1H-pyrrol-3-yl)-1,3,4-oxadiazole Moiety 222
Synthesis of 3,6-diazabicyclo[3.1.1]heptanes as novel ligands for the opioid receptors 219
6-Chloropyridazin-3-yl-derivatives active as nicotinic agents: synthesis, binding, and modeling studies 202
Structural and conformational studies of 3,8-diazabyciclo[3.2.1]octane derivatives, selective agonists of µ-opioid receptors 200
3,8-diazabicyclo[3.2.1]octane derivatives as analogues of abasilide, a class III antiarrhythmic agent 192
3-(5-phenyl-[1,3,4]oxadiazol-2-yl)-1H-benzo[g]indole and related compounds : synthesis and cytotoxic activities 191
Synthesis, molecular modelling and cytotoxicity of new 1,3,4-oxadiazoles derivatives with antimitotic activity 179
2,2,6- and 2,3,5-trimethylpiperazines as monocyclic analogues of the mu-opioid agonist 3,8-diazabicyclo[3.2.1]octanes: Synthesis, modeling, and activity 166
2,2,6- and 2,3,5-trimethypiperazines as monocyclic analogues of the mu-opioid agonis 3,8-diazabicyclo[3.2.1]octanes: synthesis, modeling and activity 162
Spirocyclopropane carboxylic acids derived from 1-tetralone and 4-chromanone and their conversion to the corresponding pyridazinones 159
Mono- and disubstituted-3,8-diazabicyclo[3.2.1]octane derivatives as analgesics structurally related to epibatidine: Synthesis, activity, and modeling 158
Synthesis, screening, and molecular modeling of new potent and selective antagonists at the alpha 1d adrenergic receptor 157
A new heterocyclic class: 2,5,6-trisubstituted-6,7-dihydro-1,3,4-oxadiazepines: A facile and general synthesis 152
Rigid congeners of arylpyridazinones. IV. Synthesis and activity of derivatives of the new heterocyclic system 9H-indeno[2,1-c]pyridazine 151
Synthesis, modelling, and mu-opioid receptor affinity of N-3(9)-arylpropenyl-N-9(3)-propionyl-3,9-diazabicyclo[3.3.1]nonanes 150
Synthesis, activity and molecular modeling of a mew series of tricyclic pyridazinones as selective aldose reductase inhibitors 148
Sintesi, attività e modelling di derivati mono- e difenilpiridazinici come potenziali inibitori dell'enzima acil-CoA colesterolo aciltrasferasi (ACAT) 147
Pyridazinones and their tricyclic congeners : chemistry and biology 147
2-(Substituted)amino-2,8-diazaspiro[4,5]decan-1,3-diones as potential muscarinic agonists: Synthesis, modeling and binding studies 147
Valutazione in vivo delle potenzialità terapeutiche di nuove molecole nel trattamento delle encefalopatie spongiformi trasmissibili 147
New congeners of antihypertensive and antithrombotic 7-amino or acetylamino substituted-4,4a-dihydro5H-indeno(1,2-c)pyridazin-3-ones 146
Synthesis, modelling and antimitotic properties of tricyclic systems characterized by 2-(5-phenyl-1H-pyrrol-3-yl)-1,3,4-oxadiazole moiety 142
Benzo(c)thiophene derivatives. IV. Synthesis and disproportionation of 1,1',3,3'-tetrahydro-1,1'-dimethoxycarbonyl-1,1'-dibenzo(c)thiophene 142
Congo red analogues as potential anti-prion agents 142
Synthesis and pharmacological evaluation of 4,4a-dihydro-5H(1)benzopyrano(4,3-c)pyridazin-3(2H)ones bioisosters of antihypertensive and antithrombotic benzo(h)cinnolinones 140
Synthesis of 3,6-diazabicyclo[3.1.1]heptanes as novel ligands for the opioids receptors 137
Sintesi e valutazione farmacologia di nuovi ligandi per il recettore dell’acido gamma-idrossi butirrico 135
Benzocondensed derivatives as rigid analogues of the -opioid agonist 3(8)-cinnamyl-8(3)-propionyl-3,8-diazabicyclo[3.2.1]octanes: synthesis, modeling, and affinity 134
A facile synthesis of 3-aryl-4-pyrazole acetic acids and of their 4,5-dihydro derivatives 133
Conformationally restricted congeners of hypothensive and platelet aggregation inhibitors 6-aryl-5-methyl-4,5-dihydro-3(2H)pyridazinones derived from 5H-indeno(1,2-c)pyridazine 133
Unexpected behaviour of the oxidizing agent sodium m-nitrobenzene sulfonate: synthesis of a new class of 5-hydroxy(1)benzopyrano4,3-cpyridazin-3(2H)ones 132
Synthesis and pharmacological evaluation of a new series of substituted benzoyl-gamma-butyrolactone derivatives 130
Interaction of 3,8-diazabicyclo (3.2.1) octanes with mu and delta opioid receptors 128
Structural and conformational studies of 3,8-diazabicyclo[3.2.1]octane derivatives, selective agonists of mu-opioid recepors 127
Sintesi ed attivita' diuretica di composti strutturalmente correlabili alla clopamide 127
Pyridazine derivatives as novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors 126
Versatility of the pyridazine system: Chemistry and biology 126
Synthesis and pharmacological evaluation of a new series of substituted benzoyl-γ-butyrolactone derivatives 126
Synthesis and pharmacological evaluation of a new class of 2-oxo-8-azaspiro(4,5)decan-1-ones as analogues of the muscarinic agonist RS-86 123
Hydroxymethylation of 2-hydroxypropiophenones in aqueous medium. Synthesis of 3-hydroxymethyl-3-methyl-4-chromanones and their conversion to 3-methyl-4-chromanone-3-acetic acids 123
Synthesis and pharmacological study of 5-aryl-6-methyl-pyridazin-3(2H)ones and related 5-aryl-6-methylpyridazin-3(2H)ones 122
Conformationally constrained congeners of 6-aryl-5-methyl-4,5-dihydro-3(2H)-pyridazinones active on the cardiovascular system: conformational studies by molecular mechanics calculations and proton NMR spectroscopy 122
Synthesis and biological evaluation of substituted benzo(h)cinnolinones and 3H-benzo(6,7)cyclohepta(1,2-c)pyridazinones: higher homologs of the antihypertensive and antithrombotic 5H-indeno(1,2-c)pyridazinones 121
Reinvestigation of the reaction of 3-hydroxy-2-methyl-1-aryl-propanones and related compounds with hydrazines and carboxylic acids 118
Synthesis of a new series of 2.8-disubstituted-2,8-diazaspiro(4,5)decan-1-ones as potential muscarinic agonists 117
Non peptidic ligands at the opioid receptor like-1 (ORL-1) 115
Phenylpiperazinylalkylamino substituted pyridazinones as potent alpha1 adrenoceptor antagonists 114
Synthesis of a new series of 2,7-diazaspiro(3,5)nonan-1-ones and study of their cholinergic properties 114
Tricyclic congeners of antihypertensive and antithrombotic 6-aryl-5-methylpyridazinones 112
Hydroxymethylation of propiophenones in aqueous medium 111
Computer-Aided structure-affinity relationships in a set of piperazine and 3,8-diazabicyclo(3.2.1)octane derivatives binding to the mu-opioid receptor 111
Tricyclic indenopyridazine derivatives: synthesis, cytotoxic activity and DNA-binding properties 110
Antinociceptive action of DBO 17 and DBO 11 in mice: two 3,8-diazabicyclo[3.2.1]octane derivatives with selective mu-opioid receptor affinity 110
Diuretic agents related to Indapamide IV. Synthesis and pharmacological activity of N(4-chloro-3-sulfamoylbenzamido)2-methyl-phenyl-pyrrolidines and N1(4-chloro-3-sulfamoylbenzoyl)N2-aryl or aralkyl-alkylhydrazines 110
Synthesis of a new series of N-substituted-3(1-alkyl/aryl-4-piperidyl)azetidin-2-ones as possible muscarinic agents 108
The opiod-receptor-like 1 (ORL-1) as a potential target for new analgesics 106
New aldose reductase inhibitors as potential agents for the prevention of long-term diabetic complications 105
Naphthalimido derivatives as antifolate thymidylate synthase inhibitors 105
Synthesis of a new series of 8-substituted-2,8-diazaspiro(4,5)decan-3-ones 104
Synthesis and pharmacological activity of 4-carbamoyl-5-aryl-6-methyl-4,5-dihydropyridazin-3(2H)ones 104
Development of pharmacophores for inhibitors of the rapid component of the cardiac delayed rectifier potassium current 102
Novel adrenoceptor antagonists with a tricyclic pyrrolodipyridazine skeleton 101
Synthesis of 1,4-disubstituted-2-methylpiperazines and study of their analgesic properties 96
Synthesis and aldose reductase inhibitory activity of a new series of benzo[h]cinnolinone derivatives 96
Tricyclic pyridazines: a versatile substrate for pharmacologically active compounds 96
Thienocycloheptapyridazines as new muscarinic agents 96
Molecular mechanics and 1H NMR conformational study of 3,8-diazabicyclo[3,2,1] octanes and related cis-2,6-dimethylpiperazines active on opioid receptors 94
Synthesis and pharmacological evaluation of thienocinnolin- 3(2H)ones, bioisosters of antihypertensive and antithrombotic benzo(h)cinnolinones 93
Reaction of 4-aroyl-2(3H)dihydrofuranones with hydroxylamine hydrochloride. Synthesis and pharmacological study of a series of 3-aryl-4,5-dihydro-4-isoxazoleacetic acids 90
Behavior of 5,6-dihydrobenzo[h]cinnolinones towards hydrazine. Synthesis of benzo[h]cinnolinones and of 4-aminobenzo[h]cinnolinones 90
Tricyclic 3-(2H)-pyridazinone derivatives : synthesis and evaluation of their antisecretory and antiulcer activity 82
Indenopyridazinone derivatives as potential antisecretory and antiulcer agents 78
Synthesis of novel diazatricyclodecanes (DTDs). Effects of structural variation at the C3′ allyl end and at the phenyl ring of the cinnamyl chain on μ-receptor affinity and opioid antinociception 76
Synthesis and mu-opioid receptor affinity of a new series of nitro substituted 3,8-diazabicyclo[3.2.1]octane derivatives 70
Totale 10.475
Categoria #
all - tutte 26.246
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 26.246


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021283 0 0 0 0 0 0 0 0 0 0 236 47
2021/2022627 53 24 2 24 74 36 30 52 45 51 119 117
2022/2023969 132 78 67 148 110 203 28 53 92 5 41 12
2023/2024406 14 45 21 7 70 19 25 39 3 47 55 61
2024/20251.411 52 86 5 160 351 24 45 157 61 76 98 296
2025/20262.342 234 146 251 237 227 173 213 209 334 193 125 0
Totale 10.475