Sfoglia per Autore
FOXG1 is responsible for the congenital variant of Rett syndrome
2008 F. Ariani, G. Hayek, D. Rondinella, R. Artuso, M. Mencarelli, A. Spanhol-Rosseto, M. Pollazzon, S. Buoni, O. Spiga, S. Ricciardi, I. Meloni, I. Longo, F. Mari, V. Broccoli, M. Zappella, A. Renieri
CDKL5 influences RNA splicing activity by its association to the nuclear speckle molecular machinery
2011 S. Ricciardi, C. Kilstrup-Nielsen, T. Bienvenu, A. Jacquette, N. Landsberger, V. Broccoli
Reduced AKT/mTOR signaling and protein synthesis dysregulation in a rett syndrome animal model
2011 S. Ricciardi, E.M. Boggio, S. Grosso, G. Lonetti, G. Forlani, G. Stefanelli, E. Calcagno, N. Morello, N. Landsberger, S. Biffo, T. Pizzorusso, M. Giustetto, V. Broccoli
CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons
2012 S. Ricciardi, F. Ungaro, M. Hambrock, N. Rademacher, G. Stefanelli, D. Brambilla, A. Sessa, C. Magagnotti, A. Bachi, E. Giarda, C. Verpelli, C. Kilstrup Nielsen, C. Sala, V. Kalscheuer, V. Broccoli
Ribosomes
2014 S. Ricciardi, F. Loreni
eIF6 anti-association activity is required for ribosome biogenesis, translational control and tumor progression
2015 D. Brina, A. Miluzio, S. Ricciardi, S. Biffo
eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription
2015 D. Brina, A. Miluzio, S. Ricciardi, K. Clarke, P.K. Davidsen, G. Viero, T. Tebaldi, N. Offenhäuser, J. Rozman, B. Rathkolb, S. Neschen, M. Klingenspor, E. Wolf, V. Gailus-Durner, H. Fuchs, M. Hrabe De Angelis, A. Quattrone, F. Falciani, S. Biffo
Eukaryotic translation initiation factor 6 is a novel regulator of reactive oxygen species-dependent megakaryocyte maturation
2015 S. Ricciardi, A. Miluzio, D. Brina, K. Clarke, M. Bonomo, R. Aiolfi, L.G. Guidotti, F. Falciani, S. Biffo
Expression and activity of eIF6 trigger Malignant Pleural Mesothelioma growth in vivo
2015 A. Miluzio, S. Oliveto, E. Pesce, L. Mutti, B. Murer, S. Grosso, S. Ricciardi, D. Brina, S. Biffo
Translational control by mTOR-independent routes: How eIF6 organizes metabolism
2016 A. Miluzio, S. Ricciardi, N. Manfrini, R. Alfieri, S. Oliveto, D. Brina, S. Biffo
MTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex
2016 M. Pema, L. Drusian, M. Chiaravalli, M. Castelli, Q. Yao, S. Ricciardi, S. Somlo, F. Qian, S. Biffo, A. Boletta
CDKL5 and shootin1 interact and concur in regulating neuronal polarization
2016 M.S. Nawaz, E. Giarda, F. Bedogni, P.L. Montanara, S. Ricciardi, D. Ciceri, T. Alberio, N. Landsberger, L. Rusconi, C. Kilstrup Nielsen
SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention
2017 P. Calamita, A. Miluzio, A. Russo, E. Pesce, S. Ricciardi, F. Khanim, C. Cheroni, R. Alfieri, M. Mancino, C. Gorrini, G. Rossetti, I. Peluso, M. Pagani, D.L. Medina, J. Rommens, S. Biffo
Data on the effects of eIF6 downmodulation on the proportions of innate and adaptive immune system cell subpopulations and on thymocyte maturation
2017 N. Manfrini, S. Ricciardi, A. Miluzio, M. Fedeli, A. Scagliola, S. Gallo, T. Adler, D.H. Busch, V. Gailus-Durner, H. Fuchs, M.H. de Angelis, S. Biffo
The Role of Eif6 in Skeletal Muscle Homeostasis Revealed by Endurance Training Co-expression Networks
2017 K. Clarke, S. Ricciardi, T. Pearson, I. Bharudin, P.K. Davidsen, M. Bonomo, D. Brina, A. Scagliola, D.M. Simpson, R.J. Beynon, F. Khanim, J. Ankers, M.A. Sarzynski, S. Ghosh, A. Pisconti, J. Rozman, M. Hrabe de Angelis, C. Bunce, C. Stewart, S. Egginton, M. Caddick, M. Jackson, C. Bouchard, S. Biffo, F. Falciani
High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+T cells in both mice and humans
2017 N. Manfrini, S. Ricciardi, A. Miluzio, M. Fedeli, A. Scagliola, S. Gallo, D. Brina, T. Adler, D.H. Busch, V. Gailus-Durner, H. Fuchs, M. Hrabě de Angelis, S. Biffo
Up-regulation of eIF6 inhibits cardiac hypertrophy induced by phenylephrine
2018 N. Romano, S. Ricciardi, P. Gallo, M. Ceci
Crosstalks between translation and metabolism in cancer
2018 S. Biffo, N. Manfrini, S. Ricciardi
A Mad2-Mediated Translational Regulatory Mechanism Promoting S-Phase Cyclin Synthesis Controls Origin Firing and Survival to Replication Stress
2018 S. Gay, D. Piccini, C. Bruhn, S. Ricciardi, P. Soffientini, W. Carotenuto, S. Biffo, M. Foiani
The eukaryotic Initiation Factor 6 (eIF6) regulates ecdysone biosynthesis by modulating translation in Drosophila
2018 A. Russo, G. Gatti, R. Alfieri, E. Pesce, K. Soanes, S. Ricciardi, M. Mancino, C. Cheroni, T. Vaccari, S. Biffo, P. Calamita
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