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Mostrati risultati da 1 a 20 di 93
Titolo Data di pubblicazione Autori Tipo File Abstract
Flavodoxin-cytochrome c interactions : circular dichroism and nuclear magnetic resonance studies 1987 De Francesco, Raffaele + Article (author) -
Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: a 2.2 A resolution structure in a hexagonal crystal form 1998 Francesco, Raffaele De + Article (author) -
Characterization of the Inhibition of Hepatitis C Virus RNA Replication by Nonnucleosides 2004 De Francesco, Raffaele + Article (author) -
The monoethyl ester of meconic acid is an active site inhibitor of HCV NS5B RNA-dependent RNA polymerase 2004 De Francesco, Raffaele + Article (author) -
HCVNS5b RNA-dependent RNA polymerase inhibitors: From alpha,gamma-diketoacids to 4,5-dihydroxypyrimidine- or 3-methyl-5-hydroxypyrimidinonecarboxylic acids : design and synthesis 2004 De Francesco, Raffaele + Article (author) -
Reduction of hepatitis C virus NS5A hyperphosphorylation by selective inhibition of cellular kinases activates viral RNA replication in cell culture 2004 De Francesco, Raffaele + Article (author) -
Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor 2004 De Francesco, Raffaele + Article (author) -
Discovery of alpha,gamma-diketo acids as potent selective and reversible inhibitors of hepatitis C virus NS5b RNA-dependent RNA polymerase 2004 De Francesco, Raffaele + Article (author) -
Challenges and successes in developing new therapies for hepatitis C 2005 De Francesco, Raffaele + Article (author) -
Interdomain communication in hepatitis C virus polymerase abolished by small molecule inhibitors bound to a novel allosteric site 2005 De Francesco, Raffaele + Article (author) -
A functionally orthogonal estrogen receptor-based transcription switch specifically induced by a nonsteroid synthetic ligand 2005 De Francesco, Raffaele + Article (author) -
HCV antiviral resistance: The impact of in vitro studies on the development of antiviral agents targeting the viral NS5B polymerase 2005 De Francesco, Raffaele + Article (author) -
Potent inhibitors of subgenomic hepatitis C virus RNA replication through optimization of indole-N-acetamide allosteric inhibitors of the viral NS5B polymerase 2005 De Francesco, Raffaele + Article (author) -
Development and preliminary optimization of indole-N-acetamide inhibitors of hepatitis C virus NS5B polymerase 2005 De Francesco, Raffaele + Article (author) -
A series of novel, potent, and selective histone deacetylase inhibitors 2006 Francesco, Raffaele De + Article (author) -
2-(2-thienyl)-5,6-dihydroxy-4-carboxypyrimidines as inhibitors of the hepatitis C virus NS5B polymerase: Discovery, SAR, modeling, and mutagenesis 2006 De Francesco, Raffaele + Article (author) -
The alpha isoform of protein kinase CKI is responsible for hepatitis C virus NS5A hyperphosphorylation 2006 De Francesco, Raffaele + Article (author) -
A structure-guided approach to an orthogonal estrogen-receptor-based gene switch activated by ligands suitable for in vivo studies 2006 De Francesco, Raffaele + Article (author) -
Advances in the development of new therapeutic agents targeting the NS3-4A serine protease or the NS5B RNA-dependent RNA polymerase of the hepatitis C virus 2007 De Francesco, Raffaele + Article (author) -
Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation 2007 De Francesco, Raffaele + Article (author) -
Mostrati risultati da 1 a 20 di 93
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