Sfoglia per Autore
LXR (liver X receptor) and HNF-4 (hepatocyte nuclear factor-4): key regulators in reverse cholesterol transport
2004 M. Crestani, E. De Fabiani, D. Caruso, N. Mitro, F. Gilardi, A. B. Vigil Chacon, R. Patelli, C. Godio, G. Galli
Bile acid signaling to the nucleus: finding new connections in the transcriptional regulation of metabolic pathways
2004 E. De Fabiani, N. Mitro, C. Godio, F. Gilardi, D. Caruso, M. Crestani
Histone deacetylases regulate bile acid biosynthesis
2005 C. Godio, N. Mitro, E. Scotti, E. De Fabiani, D. Caruso, M. Crestani
Synthesis, biological evaluation, and molecular modeling investigation of new chiral fibrates with PPAR alpha and PPAR gamma agonist activity
2005 A. Pinelli, C. Godio, A. Laghezza, N. Mitro, G. Fracchiolla, V. Tortorella, A. Lavecchia, E. Novellino, J.C. Fruchart, B. Staels, M. Crestani, F. Loiodice
Inhibition of histone deacetylases for the treatment of hyperlipidemias and prevention of atherosclerosis and cardiovascular diseases
2005 M. Crestani, C. Godio, N. Mitro
Hepatic expression of PPAR-gamma coactivator 1 (PGC-1) is reduced in human cholelithiasis
2006 M. Bertolotti, C. Gabbi, C. Anzivino, N. Mitro, C. Godio, E. De Fabiani, M. Crestani, L. Carulli, M. Del Puppo, A. Rossi, P. Loria, N. Carulli
Decreased hepatic expression of PPAR-gamma coactivator-1 in cholesterol cholelithiasis
2006 M. Bertolotti, C. Gabbi, C. Anzivino, N. Mitro, C. Godio, E. De Fabiani, M. Crestani, M. Del Puppo, M. Ricchi, L. Carulli, A. Rossi, P. Loria, N. Carulli
Bile acids repress cholesterol 7 alpha-hydroxylase gene transcription by recruiting histone deacetylases
2006 C. Godio, N. Mitro, E. Scotti, E. De Fabiani, D. Caruso, M. Crestani
Identification of novel dual Peroxisome Proliferator-Activated Receptor alpha/gamma ligands and characterization of their biochemical properties by 3D structural studies
2006 C. Godio, V. Cafiero, N. Mitro, F. Loiodice, A. Lavecchia, E. Novellino, V.T.G. Pochetti, F. Mazza, M. Crestani
[4-(2H-1,2,3-benzotriazol-2-yl)phenoxy]alkanoic acids as agonists of peroxisome proliferator-activated receptors (PPARs)
2006 A. Sparatore, C. Godio, E. Perrino, S. Romeo, B. Staels, J.C. Fruchart, M. Crestani
Identification of histone deacetylase 7 as a new target for treatment of hypercholesterolemia
2006 N. Mitro, C. Godio, E. Scotti, E. Gers, E. De Fabiani, A.B. Vigil Chacon, D. Caruso, M. Crestani
3D structure and biological activity of novel dual peroxisome proliferator-activated receptors alpha/gamma ligands
2006 C. Godio, V. Cafiero, N. Mitro, F. Loiodice, A. Lavecchia, E. Novellino, V. Tortorella, G. Pochetti, F. Mazza, M. Crestani
The recruitment of histone deacetylases induced by bile acids inhibits trascription of cholesterol 7alpha-hydroxylase gene (CYP7A1)
2006 E. Scotti, C. Godio, N. Mitro, E. Gers, E. De Fabiani, A.B. Vigil Chacon, D. Caruso, M. Crestani
Analysis of nuclear factors dynamically exchanged on the cholesterol 7 alpha-hydroxylase gene reveals a target for treatment of hypercholesterolemia
2006 N. Mitro, C. Godio, E. Scotti, E. Gers, E. De Fabiani, A.B. Vigil Chacon, D. Caruso, M. Crestani
Insights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor gamma ligand-binding domain in the complex with two enantiomeric ligands
2007 G. Pochetti, C. Godio, N. Mitro, D. Caruso, A. Galmozzi, S. Scurati, F. Loiodice, G. Fracchiolla, P. Tortorella, A. Laghezza, A. Lavecchia, E. Novellino, F. Mazza, M. Crestani
Age-related changes in bile acid synthesis and hepatic nuclear receptor expression
2007 M. Bertolotti, C. Gabbi, C. Anzivino, M. Crestani, N. Mitro, M. Del Puppo, C. Godio, E. De Fabiani, D. Macchioni, L. Carulli, A. Rossi, M. Ricchi, P. Loria, N. Carulli
Effects of histone deacetylase inhibitors on energy metabolism
2007 E. Gers, A. Galmozzi, F. Gilardi, N. Mitro, J. Krneta, C. Godio, E. Scotti, E. De Fabiani, D. Caruso, M. Crestani
On the mechanism of partial agonist : crystal structures of the peroxisome proliferator-activated receptor gamma ligand-binding domain in the complex with two enantiomeric ligands
2007 M. Crestani, G. Pochetti, C. Godio, N. Mitro, D. Caruso, A. Galmozzi, S. Scurati, F. Loiodice, G. Fracchiolla, P. Tortorella, A. Laghezza, A. Lavecchia, E. Novellino, F. Mazza
Nuclear receptors, coregulators and chromatin in the control of gene regulation and cellular metabolism
2007 N. Mitro, F. Gilardi, E. Scotti, C. Godio, E. De Fabiani, A. Galmozzi, E. Gers, D. Caruso, M. Crestani
Insights in the regulation of cholesterol 7alpha-hydroxylase gene reveal a target for modulating bile acid synthesis
2007 N. Mitro, C. Godio, E. De Fabiani, E. Scotti, A. Galmozzi, F. Gilardi, D. Caruso, A.B. Vigil Chacon, M. Crestani
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