In this paper, we aim at rethinking the concept of obesity in a way that better captures the connection between underlying medical aspects, on the one hand, and an individual’s developmental history, on the other. Our proposal rests on the idea that obesity is not to be understood as a phenotypic trait or character; rather, obesity represents one of the many possible states of a more complex phenotypic trait that we call ‘energy metabolism.’ We argue that this apparently simple conceptual shift can help solve important theoretical misconceptions regarding the genetics, epigenetics, and development of obesity. In addition, we show that our proposal can be fruitfully paired with the concept of developmental channeling of a trait, which connects to the study of the plasticity and canalization of complex traits. Finally, we discuss the potential impact of our approach on the assessment, treatment, and social narratives of obesity.

From Obesity to Energy Metabolism: Ontological Perspectives on the Metrics of Human Bodies / D. Serpico, A. Borghini. - In: TOPOI. - ISSN 0167-7411. - (2020). [Epub ahead of print] [10.1007/s11245-020-09722-1]

From Obesity to Energy Metabolism: Ontological Perspectives on the Metrics of Human Bodies

D. Serpico;A. Borghini
2020

Abstract

In this paper, we aim at rethinking the concept of obesity in a way that better captures the connection between underlying medical aspects, on the one hand, and an individual’s developmental history, on the other. Our proposal rests on the idea that obesity is not to be understood as a phenotypic trait or character; rather, obesity represents one of the many possible states of a more complex phenotypic trait that we call ‘energy metabolism.’ We argue that this apparently simple conceptual shift can help solve important theoretical misconceptions regarding the genetics, epigenetics, and development of obesity. In addition, we show that our proposal can be fruitfully paired with the concept of developmental channeling of a trait, which connects to the study of the plasticity and canalization of complex traits. Finally, we discuss the potential impact of our approach on the assessment, treatment, and social narratives of obesity.
Definition of obesity; Developmental canalization; Epigenetics of obesity; Genetics of obesity; Obesity; Obesity and public health;
Settore M-FIL/05 - Filosofia e Teoria dei Linguaggi
Settore M-FIL/01 - Filosofia Teoretica
Settore M-FIL/02 - Logica e Filosofia della Scienza
   Dipartimenti di Eccellenza 2018-2022 - Dipartimento di FILOSOFIA
   MINISTERO DELL'ISTRUZIONE E DEL MERITO
2020
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/765641
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