Sialolithiasis represents the most common disorders of salivary glands in middle-aged patients. It has been hypothesized that the retrograde migration of bacteria from the oral cavity to gland ducts may facilitate the formation of stones. Thus, in the present study, a microbiome characterization of salivary calculi was performed to evaluate the abundance and the potential correlations between microorganisms constituting the salivary calculi microbiota. Our data supported the presence of a core microbiota of sialoliths constituted principally by Streptococcus spp., Fusobacterium spp. and Eikenella spp., along with the presence of important pathogens commonly involved in infective sialoadenitis.
Salivary calculi microbiota: new insights into microbial networks and pathogens reservoir / R. De Grandi, P. Capaccio, A. Bidossi, M. Bottagisio, L. Drago, S. Torretta, L. Pignataro, E. De Vecchi. - In: MICROBES AND INFECTION. - ISSN 1286-4579. - (2018 Oct 30). [Epub ahead of print] [10.1016/j.micinf.2018.10.002]
Salivary calculi microbiota: new insights into microbial networks and pathogens reservoir
P. CapaccioSecondo
;M. Bottagisio;L. Drago;S. Torretta;L. PignataroPenultimo
;E. De VecchiUltimo
2018
Abstract
Sialolithiasis represents the most common disorders of salivary glands in middle-aged patients. It has been hypothesized that the retrograde migration of bacteria from the oral cavity to gland ducts may facilitate the formation of stones. Thus, in the present study, a microbiome characterization of salivary calculi was performed to evaluate the abundance and the potential correlations between microorganisms constituting the salivary calculi microbiota. Our data supported the presence of a core microbiota of sialoliths constituted principally by Streptococcus spp., Fusobacterium spp. and Eikenella spp., along with the presence of important pathogens commonly involved in infective sialoadenitis.File | Dimensione | Formato | |
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