This work describes an extensive numerical investigation of thermal water delivery for the treatment of inflammatory disorders in the human nasal cavity. The numerical simulation of the multiphase air-droplets flow is based upon the Large Eddy Simulation (LES) technique, with droplets of thermal water described via a Lagrangian approach. Droplet deposition is studied for different sizes of water droplets, corresponding to two different thermal treatments, i.e. aerosol and inhalation. Numerical simulations are conducted on a patient-specific anatomy, employing two different grid sizes, under steady inspiration at two breathing intensities. The results are compared with published in vivo and in vitro data. The effectiveness of the various thermal treatments is then assessed qualitatively and quantitatively, by a detailed analysis of the deposition patterns of the droplets. Discretization effects on the deposition dynamics are addressed. The level of detail of the present work, together with the accuracy afforded by the LES approach, leads to an improved understanding of how the mixture of air-water droplets is distributed within the nose and the paranasal sinuses.

Numerical simulation of thermal water delivery in the human nasal cavity / V. Covello, C. Pipolo, A. Saibene, G. Felisati, M. Quadrio. - In: COMPUTERS IN BIOLOGY AND MEDICINE. - ISSN 0010-4825. - 100(2018), pp. 62-73. [10.1016/j.compbiomed.2018.06.029]

Numerical simulation of thermal water delivery in the human nasal cavity

V. Covello
Primo
;
C. Pipolo
Secondo
;
A. Saibene;G. Felisati;
2018

Abstract

This work describes an extensive numerical investigation of thermal water delivery for the treatment of inflammatory disorders in the human nasal cavity. The numerical simulation of the multiphase air-droplets flow is based upon the Large Eddy Simulation (LES) technique, with droplets of thermal water described via a Lagrangian approach. Droplet deposition is studied for different sizes of water droplets, corresponding to two different thermal treatments, i.e. aerosol and inhalation. Numerical simulations are conducted on a patient-specific anatomy, employing two different grid sizes, under steady inspiration at two breathing intensities. The results are compared with published in vivo and in vitro data. The effectiveness of the various thermal treatments is then assessed qualitatively and quantitatively, by a detailed analysis of the deposition patterns of the droplets. Discretization effects on the deposition dynamics are addressed. The level of detail of the present work, together with the accuracy afforded by the LES approach, leads to an improved understanding of how the mixture of air-water droplets is distributed within the nose and the paranasal sinuses.
Computational fluid dynamics; Large eddy simulation; Thermal waters; Computer Science Applications; 1707; Computer Vision and Pattern Recognition; Health Informatics
Settore MED/31 - Otorinolaringoiatria
2018
Article (author)
File in questo prodotto:
File Dimensione Formato  
numerical simulation of thermal water (2018).pdf

accesso riservato

Tipologia: Publisher's version/PDF
Dimensione 3.57 MB
Formato Adobe PDF
3.57 MB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/597788
Citazioni
  • ???jsp.display-item.citation.pmc??? 4
  • Scopus 11
  • ???jsp.display-item.citation.isi??? 10
social impact