The present invention relates to a method for the production of tenocytes, highly specialized cells that form tendons connective tissues, starting from mammalian mesenchymal stem cells. Moreover, the invention relates to a method for the characterization of tenocytes and mammalian mesenchymal stem cells. It is known that tendon damages can seriously and permanently impair the mobility and functionality of an articulation. This kind of lesions frequently occurs in athletes or race animals that subject their tendons to heavy and sustained efforts due to their physical activity. It is known that race horses suffer from damages to limb tendons and that this kind of accident can lead, as an extreme consequence, to put the animals down. The invention describes an innovative therapeutic method for such tendons damages.

New method for in vitro production of tenocytes / F. Cremonesi, P. Mariani, S. Violini.

New method for in vitro production of tenocytes

F. Cremonesi
Primo
;
2010

Abstract

The present invention relates to a method for the production of tenocytes, highly specialized cells that form tendons connective tissues, starting from mammalian mesenchymal stem cells. Moreover, the invention relates to a method for the characterization of tenocytes and mammalian mesenchymal stem cells. It is known that tendon damages can seriously and permanently impair the mobility and functionality of an articulation. This kind of lesions frequently occurs in athletes or race animals that subject their tendons to heavy and sustained efforts due to their physical activity. It is known that race horses suffer from damages to limb tendons and that this kind of accident can lead, as an extreme consequence, to put the animals down. The invention describes an innovative therapeutic method for such tendons damages.
Università degli Studi di Milano
Fonadazione Parco Tecnologico Lodi
WO2010/007542
PCT/IB2009/052542
21-gen-2010
Mesenchymal stem cells ; tenocytes in vitro derivation ; tendon injuries ; horse
Settore VET/10 - Clinica Ostetrica e Ginecologia Veterinaria
http://sobjprd.questel.fr/sobj/servlet/get_pds/WO201007542A2.pdf?userid=qptui001&type=0&pdfid=18779030&ekey=1187&id=1661902053
New method for in vitro production of tenocytes / F. Cremonesi, P. Mariani, S. Violini.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/55848
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