A tumor reaching the size of 1 cm(3) (approximately 1 g wet weight) is commonly assumed to contain 1 x 10(9) cells. This paper comments on the probable origin of this "magic" number and on some possible reasons why it has remained in use until now. However, mostly in epithelial tumors (85% of all human tumors) a cell number one order of magnitude smaller would be more realistic.
Does the cell number 10(9) still really fit one gram of tumor tissue? / U. Del Monte. - In: CELL CYCLE. - ISSN 1538-4101. - 8:3(2009 Feb 01), pp. 505-506.
Does the cell number 10(9) still really fit one gram of tumor tissue?
U. Del MontePrimo
2009
Abstract
A tumor reaching the size of 1 cm(3) (approximately 1 g wet weight) is commonly assumed to contain 1 x 10(9) cells. This paper comments on the probable origin of this "magic" number and on some possible reasons why it has remained in use until now. However, mostly in epithelial tumors (85% of all human tumors) a cell number one order of magnitude smaller would be more realistic.
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