Combining chemicals. Malaria is one of the most widespread parasitic infections in the world, however, the unavailability of a vaccine and the spread and intensification of drug resistance over the past 15-20 years have led to a dramatic decline in the efficacy of the most affordable antimalarial drugs. Herein, the development of "double-drugs" to tackle inhibition of P. falciparum growth is discussed. (Chemical Equation Presented).
Atovaquone-statine "Double-Drugs" with high antiplasmodial activity / S. Romeo, S. Parapini, M. Dell'Agli, N. Vaiana, P. Magrone, G. Galli, A.C. Sparatore, D. Taramelli, E.A. Bosisio. - In: CHEMMEDCHEM. - ISSN 1860-7179. - 3:3(2008), pp. 418-420. [10.1002/cmdc.200700166]
Atovaquone-statine "Double-Drugs" with high antiplasmodial activity
S. RomeoPrimo
;S. ParapiniSecondo
;M. Dell'Agli;N. Vaiana;G. Galli;A.C. Sparatore;D. TaramelliPenultimo
;E.A. BosisioUltimo
2008
Abstract
Combining chemicals. Malaria is one of the most widespread parasitic infections in the world, however, the unavailability of a vaccine and the spread and intensification of drug resistance over the past 15-20 years have led to a dramatic decline in the efficacy of the most affordable antimalarial drugs. Herein, the development of "double-drugs" to tackle inhibition of P. falciparum growth is discussed. (Chemical Equation Presented).
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