Rheumatic diseases in women of childbearing years may necessitate drug treatment during a pregnancy, to control maternal disease activity and to ensure a successful pregnancy outcome. This survey is based on a consensus workshop of international experts discussing effects of anti-inflammatory, immunosuppressive and biological drugs during pregnancy and lactation. In addition, effects of these drugs on male and female fertility and possible long-term effects on infants exposed to drugs antenatally are discussed where data were available. Recommendations for drug treatment during pregnancy and lactation are given.
Anti-inflammatory and immunosuppressive drugs and reproduction / M. Østensen, M. Khamashta, M. Lockshin, A. Parke, A. Brucato, H. Carp, A. Doria, R. Rai, P. Meroni, I. Cetin, R. Derksen, W. Branch, M. Motta, C. Gordon, G. Ruiz-Irastorza, A. Spinillo, D. Friedman, R. Cimaz, A. Czeizel, J.C. Piette, R. Cervera, R.A. Levy, M. Clementi, S. De Carolis, M. Petri, Y. Shoenfeld, D. Faden, G. Valesini, A. Tincani. - In: ARTHRITIS RESEARCH & THERAPY. - ISSN 1478-6354. - 8:3(2006), pp. 1957.209-1957.228.
Anti-inflammatory and immunosuppressive drugs and reproduction
A. Brucato;P. Meroni;I. Cetin;R. Cimaz;
2006
Abstract
Rheumatic diseases in women of childbearing years may necessitate drug treatment during a pregnancy, to control maternal disease activity and to ensure a successful pregnancy outcome. This survey is based on a consensus workshop of international experts discussing effects of anti-inflammatory, immunosuppressive and biological drugs during pregnancy and lactation. In addition, effects of these drugs on male and female fertility and possible long-term effects on infants exposed to drugs antenatally are discussed where data were available. Recommendations for drug treatment during pregnancy and lactation are given.
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