Thirtyfour subjects affected by chronic obstructive lung disease (COPD) all of whom with a PaO2>60 mm Hg, have been studied along a 42 month period. At the enrollment 19/34 (55.8%) presented nocturnal desaturations (NOD). A stable hypoxemia (PaO2<55 mmHg) developed in 10/34 (29.4%), who were treated with LTOT: 9/10 had NOD. The patients in LTOT showed at enrollment the lowest FEV1 and highest PaCO2, together with a higher REM-associated NOD; their FEV1 declined more rapidly along the time (significantly). In conclusion REM-associated NOD can be a further risk factor or favour chronic respiratory failure.
Correlazione tra la desaturazione notturna REM-collegata e l'evoluzione della malattia in pazienti con broncopneumopatia cronica ostruttiva / M. Sergi, S. Colombo, G. Cavallaro, S. Adamante, E. Bucchioni, F. Fanfulla, V. Fasano. - In: GIMT. GIORNALE ITALIANO DELLE MALATTIE DEL TORACE. - ISSN 1127-0810. - 57:2(2003 Feb), pp. 124-129.
Correlazione tra la desaturazione notturna REM-collegata e l'evoluzione della malattia in pazienti con broncopneumopatia cronica ostruttiva
V. Fasano
2003
Abstract
Thirtyfour subjects affected by chronic obstructive lung disease (COPD) all of whom with a PaO2>60 mm Hg, have been studied along a 42 month period. At the enrollment 19/34 (55.8%) presented nocturnal desaturations (NOD). A stable hypoxemia (PaO2<55 mmHg) developed in 10/34 (29.4%), who were treated with LTOT: 9/10 had NOD. The patients in LTOT showed at enrollment the lowest FEV1 and highest PaCO2, together with a higher REM-associated NOD; their FEV1 declined more rapidly along the time (significantly). In conclusion REM-associated NOD can be a further risk factor or favour chronic respiratory failure.Pubblicazioni consigliate
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