Objective: To analyze the relationship between onion and garlic intake and benign prostatic hyperplasia (BPH), using data from a multicenter case-control study conducted in Italy. Methods: A multicenter case-control study of 1369 patients with BPH and 1451 controls, admitted to the same hospitals for a wide spectrum of acute, non-neoplastic conditions, was conducted in Italy between 1991 and 2002. Information was collected by trained interviewers using a validated and reproducible food frequency questionnaire. Multivariate odds ratios (ORs) and 95% confidence intervals (CIs) were obtained after allowance for recognized confounding factors and energy intake. Results: Compared with nonusers, the multivariate ORs for the highest category of onion and garlic intake were 0.41 (95% CI 0.24 to 0.72) and 0.72 (95% CI 0.57 to 0.91), respectively. The combined OR for frequent users versus nonusers of both onion and garlic was 0.65 (95% CI 0.49 to 0.86). The inverse relationships were consistent across age strata. Conclusions: This uniquely large data set from European populations showed an inverse association between allium vegetable consumption and BPH.
Onion and garlic intake and the odds of benign prostatic hyperplasia / C. Galeone, C. Pelucchi, R. Talamini, E. Negri, L. Dal Maso, M. Montella, V. Ramazzotti, S. Franceschi, C. La Vecchia. - In: UROLOGY. - ISSN 0090-4295. - 70:4(2007), pp. 672-676.
Onion and garlic intake and the odds of benign prostatic hyperplasia
C. GaleonePrimo
;C. Pelucchi;E. Negri;C. La VecchiaUltimo
2007
Abstract
Objective: To analyze the relationship between onion and garlic intake and benign prostatic hyperplasia (BPH), using data from a multicenter case-control study conducted in Italy. Methods: A multicenter case-control study of 1369 patients with BPH and 1451 controls, admitted to the same hospitals for a wide spectrum of acute, non-neoplastic conditions, was conducted in Italy between 1991 and 2002. Information was collected by trained interviewers using a validated and reproducible food frequency questionnaire. Multivariate odds ratios (ORs) and 95% confidence intervals (CIs) were obtained after allowance for recognized confounding factors and energy intake. Results: Compared with nonusers, the multivariate ORs for the highest category of onion and garlic intake were 0.41 (95% CI 0.24 to 0.72) and 0.72 (95% CI 0.57 to 0.91), respectively. The combined OR for frequent users versus nonusers of both onion and garlic was 0.65 (95% CI 0.49 to 0.86). The inverse relationships were consistent across age strata. Conclusions: This uniquely large data set from European populations showed an inverse association between allium vegetable consumption and BPH.Pubblicazioni consigliate
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