Fricke gel dosimetry for 3D imaging of absorbed dose in radiotherapy

The overall aim of this thesis was to develop improvements for 3D dosimetry system, based on Fricke solution, in order to achieve accurate 3D absorbed dose distributions by means of visible light transmittance analysis. Such a system would represent a useful tool for 3D treatment planning verification. In particular, the main objectives were: To make a Fricke gel dosimeter selecting proper gelling substance and optimizing gel quantity according to the dosimeter response. To develop a Fricke gel dosimeter preparation protocol in order to establish an optimal elaboration process. To evaluate the characteristics of the Fricke gel dosimeter for dose distribution measurements. To reduce the uncertainties in dose distribution determination using Fricke gel dosimeters. To study the diffusion properties of the Fricke gel dosimeter, allowing a comparison with alternative non-diffusive polymer gel.