The nasal respiratory mucosa of the rabbit has a leaky epithelium actively transporting polypeptides by a specific transcytosis probably involved in sampling antigens. The transfer displays saturation kinetics and is abolished by metabolic inhibitors, actin filamet and microtubule disassemblers, inhibitors of vesicle fusion, and receptor recycling;it accepts polypeptide-covered but not uncovered nanoparticles.
Endocytosis of polypeptides in the nasal respiratory mucosa of the rabbit [Recensione] / D. Cremaschi, C. Porta, R. Ghirardelli. - In: NEWS IN PHYSIOLOGICAL SCIENCES. - ISSN 0886-1714. - 12:5(1997), pp. 219-225. [10.1152/physiologyonline.1997.12.5.219]
Endocytosis of polypeptides in the nasal respiratory mucosa of the rabbit
D. CremaschiPrimo
;C. PortaSecondo
;
1997
Abstract
The nasal respiratory mucosa of the rabbit has a leaky epithelium actively transporting polypeptides by a specific transcytosis probably involved in sampling antigens. The transfer displays saturation kinetics and is abolished by metabolic inhibitors, actin filamet and microtubule disassemblers, inhibitors of vesicle fusion, and receptor recycling;it accepts polypeptide-covered but not uncovered nanoparticles.
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