Latex beads coated with secretory immunoglobulin (IgA) instilled into mouse intestinal loops are taken up by M cells present in Peyer's patch follicle-associated epithelial tissue. Bead adsorption and uptake is greater at the edge compared with the apex of follicle domes. Coating beads with bovine serum albumin (BSA) causes a fourfold reduction in adsorption and a twentyfold reduction in uptake. Results demonstrate selectivity between adsorption and uptake and between the ability of different proteins to facilitate uptake.
Confocal analysis of fluorescent bead uptake by mouse Peyer's patch follicle-associated M cells / C. Porta, P.S. James, A.D. Phillips, T.C. Savidge, M.W. Smith, D. Cremaschi. - In: EXPERIMENTAL PHYSIOLOGY. - ISSN 0958-0670. - 77:6(1992), pp. 929-932. [10.1113/expphysiol.1992.sp003662]
Confocal analysis of fluorescent bead uptake by mouse Peyer's patch follicle-associated M cells
C. PortaPrimo
;D. CremaschiUltimo
1992
Abstract
Latex beads coated with secretory immunoglobulin (IgA) instilled into mouse intestinal loops are taken up by M cells present in Peyer's patch follicle-associated epithelial tissue. Bead adsorption and uptake is greater at the edge compared with the apex of follicle domes. Coating beads with bovine serum albumin (BSA) causes a fourfold reduction in adsorption and a twentyfold reduction in uptake. Results demonstrate selectivity between adsorption and uptake and between the ability of different proteins to facilitate uptake.Pubblicazioni consigliate
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