The authors describe an approach using ring-closing metathesis (RCM) to synthesize versatile coumarin derivs. that present appropriate substitutions both at the arom. and at the a,b-unsatd. lactone ring. The obtained compds. can be used as mol. scaffolds suitable for further diversifications through a combinatorial approach.
Simple synthesis of versatile coumarin scaffolds / L. Polito, M. Cravini, L. Poletti, L. Lay. - In: SYNTHETIC COMMUNICATIONS. - ISSN 0039-7911. - 36:15(2006), pp. 2203-2209.
Simple synthesis of versatile coumarin scaffolds
L. PolitoPrimo
;M. CraviniSecondo
;L. PolettiPenultimo
;L. LayUltimo
2006
Abstract
The authors describe an approach using ring-closing metathesis (RCM) to synthesize versatile coumarin derivs. that present appropriate substitutions both at the arom. and at the a,b-unsatd. lactone ring. The obtained compds. can be used as mol. scaffolds suitable for further diversifications through a combinatorial approach.
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