Functionalized bicyclic lactams serve as building blocks for the synthesis of conformationally constrained peptides. A route to these building blocks is described based on the stereoselective alkylation of an appropriate azabicycloalkane; all possible diastereoisomers can be obtained stereoselectively.

Synthesis of functionalized azabicycloalkane amino acids as dipeptide mimics / L. MANZONI, L. BELVISI, E. DICARLO, A. FORNI, D. INVERNIZZI, C. SCOLASTICO. - In: SYNTHESIS. - ISSN 0039-7881. - :7(2006), pp. 1133-1140.

Synthesis of functionalized azabicycloalkane amino acids as dipeptide mimics

L. BELVISI
Secondo
;
E. DICARLO;D. INVERNIZZI
Penultimo
;
C. SCOLASTICO
Ultimo
2006

Abstract

Functionalized bicyclic lactams serve as building blocks for the synthesis of conformationally constrained peptides. A route to these building blocks is described based on the stereoselective alkylation of an appropriate azabicycloalkane; all possible diastereoisomers can be obtained stereoselectively.
Alkylations; Bicyclic compounds; Diastereoselective synthesis; Lactams; Peptidomimetics
Settore CHIM/06 - Chimica Organica
2006
http://www.thieme-connect.com/ejournals/html/synthesis/doi/10.1055/s-2006-926370
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/25751
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