The effect of Stevia extracts on in vitro Streptococcus mutans biofilm formation and in vivo plaque pH was evaluated in this paper. Three 10% solutions containing stevioside, rebaudioside A or sucrose were prepared. MTT assay was used to evaluate microbiological counts in vitro. Twenty volunteers rinsed for 1 min with each solutions, and plaque pH was measured at 7 time points after each rinse. Higher in vitro S. mutans biofilm formation was observed in sucrose solution (p < 0.01). After 5, 10, 15 and 30 min, the sucrose in vivo rinse produced a statistically significantly lower pH value compared to the Stevia extracts (F = 99.45, p < 0.01).Stevia extracts can be considered nonacidogenic.
An in vitro and in vivo Comparison of the Effect of Stevia rebaudiana Extracts on Different Caries-Related Variables : A Randomized Controlled Trial Pilot Study / E. Brambilla, M.G. Cagetti, A. Ionescu, G. Campus, P. Lingström. - In: CARIES RESEARCH. - ISSN 0008-6568. - 48:1(2014), pp. 19-23. [10.1159/000351650]
An in vitro and in vivo Comparison of the Effect of Stevia rebaudiana Extracts on Different Caries-Related Variables : A Randomized Controlled Trial Pilot Study
E. Brambilla;M.G. Cagetti;A. Ionescu;
2014
Abstract
The effect of Stevia extracts on in vitro Streptococcus mutans biofilm formation and in vivo plaque pH was evaluated in this paper. Three 10% solutions containing stevioside, rebaudioside A or sucrose were prepared. MTT assay was used to evaluate microbiological counts in vitro. Twenty volunteers rinsed for 1 min with each solutions, and plaque pH was measured at 7 time points after each rinse. Higher in vitro S. mutans biofilm formation was observed in sucrose solution (p < 0.01). After 5, 10, 15 and 30 min, the sucrose in vivo rinse produced a statistically significantly lower pH value compared to the Stevia extracts (F = 99.45, p < 0.01).Stevia extracts can be considered nonacidogenic.File | Dimensione | Formato | |
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