A three-component sequential process consisting in (1) in situ formation of carbodiimides by Staudinger reaction, (2) reaction with 2-(bromomethyl)-3-aryl-2-propenoic acids, and (3) final cyclization of the resulting N-acylurea intermediates in order to obtain the synthesis of an array of N,N0-disubstituted 5- arylidenedihydropyrimidine-2,4-dione under mild conditions is presented.
Three-component sequential synthesis of N,N0-disubstituted 5-arylidenedihydropyrimidine-2,4-dione / M.C. Bellucci, A. Volonterio. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 53:35(2012 Jun 29), pp. 4733-4737. [10.1016/j.tetlet.2012.06.109]
Three-component sequential synthesis of N,N0-disubstituted 5-arylidenedihydropyrimidine-2,4-dione
M.C. BellucciPrimo
;
2012
Abstract
A three-component sequential process consisting in (1) in situ formation of carbodiimides by Staudinger reaction, (2) reaction with 2-(bromomethyl)-3-aryl-2-propenoic acids, and (3) final cyclization of the resulting N-acylurea intermediates in order to obtain the synthesis of an array of N,N0-disubstituted 5- arylidenedihydropyrimidine-2,4-dione under mild conditions is presented.File | Dimensione | Formato | |
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