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|Title: ||Semen preparation by standard swim-up versus swim-up with test yolk buffer incubation in intrauterine insemination: a randomized study|
|Authors: ||PARAZZINI, FABIO (Second to last author)|
CROSIGNANI, PIERGIORGIO (Last author)
|Abstract: ||In order to compare the standard swim-up semen preparation with and without test yolk buffer (TYB) incubation in intrauterine insemination (IUI), we conducted a prospective multicentre randomized trial. A total of 121 infertile couples with male factor (n = 52) or unexplained infertility (n = 69) was randomly assigned to two groups following ovulation induction. Semen was prepared by standard swim-up in group A (n = 64) and by swim-up followed by TYB incubation in group B (n = 57). A maximum of two IUI cycles was performed. A total of 104 cycles was performed in the swim-up group and 90 in the TYB group. Overall, 15 pregnancies were achieved in group A and 23 in group B, with an overall pregnancy rate of 24.8 and 50.0% per patient respectively (chi2(1), P < 0.05). In the male factor group, pregnancy was achieved in six out of 24 couples (25%) following standard swim-up and in six out of 28 (21.4%) following swim-up and TYB incubation (chi2(1), not significant). In the unexplained infertility group, pregnancy was recorded in nine out of 40 couples (22.5%) following standard swim-up and in 17 out of 29 couples (58.6%) following swim-up and TYB incubation (chi2(1), P < 0.05).|
|Keywords: ||Infertility ; Insemination, Artificial, Homologous ; Infertility, Male ; Humans ; Glucose ; Sperm Motility ; Pregnancy ; Ovulation Induction ; Prospective Studies ; Semen ; Tromethamine ; Female ; Male|
|MIUR subjects: ||MED/40 - Ginecologia e Ostetricia|
|Publication date: ||Jul-1998|
|Digital Object Identifier (DOI): ||10.1093/humrep/13.7.1859|
|Citation: ||Semen preparation by standard swim-up versus swim-up with test yolk buffer incubation in intrauterine insemination: a randomized study / G. Ragni, L. De Lauretis, G. D'Ambrogio, S. Pellegrini, P. Maggioni, W. Vegetti, L. Perotti, A. Dalla Serra, F. Parazzini, P. G. Crosignani. - In: Human reproduction. - ISSN 0268-1161. - ISSN 1460-2350. - 13:7(1998 Jul), pp. 1859-1863.|
|Pubmed identifier: ||9740439|
|ISI identifier: ||000075324200029|
|Type: ||Article (author)|
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