Università degli Studi di Milano   Archivio Istituzionale della Ricerca
Please use this identifier to cite or link to this item: http://hdl.handle.net/2434/206522

Title: Semen preparation by standard swim-up versus swim-up with test yolk buffer incubation in intrauterine insemination: a randomized study
Authors: PARAZZINI, FABIO (Second to last author)
CROSIGNANI, PIERGIORGIO (Last author)
Abstract: In order to compare the standard swim-up semen preparation with and without test yolk buffer (TYB) incubation in intrauterine insemination (IUI), we conducted a prospective multicentre randomized trial. A total of 121 infertile couples with male factor (n = 52) or unexplained infertility (n = 69) was randomly assigned to two groups following ovulation induction. Semen was prepared by standard swim-up in group A (n = 64) and by swim-up followed by TYB incubation in group B (n = 57). A maximum of two IUI cycles was performed. A total of 104 cycles was performed in the swim-up group and 90 in the TYB group. Overall, 15 pregnancies were achieved in group A and 23 in group B, with an overall pregnancy rate of 24.8 and 50.0% per patient respectively (chi2(1), P < 0.05). In the male factor group, pregnancy was achieved in six out of 24 couples (25%) following standard swim-up and in six out of 28 (21.4%) following swim-up and TYB incubation (chi2(1), not significant). In the unexplained infertility group, pregnancy was recorded in nine out of 40 couples (22.5%) following standard swim-up and in 17 out of 29 couples (58.6%) following swim-up and TYB incubation (chi2(1), P < 0.05).
Keywords: Infertility ; Insemination, Artificial, Homologous ; Infertility, Male ; Humans ; Glucose ; Sperm Motility ; Pregnancy ; Ovulation Induction ; Prospective Studies ; Semen ; Tromethamine ; Female ; Male
MIUR subjects: MED/40 - Ginecologia e Ostetricia
Publication date: Jul-1998
Digital Object Identifier (DOI): 10.1093/humrep/13.7.1859
Citation: Semen preparation by standard swim-up versus swim-up with test yolk buffer incubation in intrauterine insemination: a randomized study / G. Ragni, L. De Lauretis, G. D'Ambrogio, S. Pellegrini, P. Maggioni, W. Vegetti, L. Perotti, A. Dalla Serra, F. Parazzini, P. G. Crosignani. - In: Human reproduction. - ISSN 0268-1161. - ISSN 1460-2350. - 13:7(1998 Jul), pp. 1859-1863.
Pubmed identifier: 9740439
ISI identifier: 000075324200029
Type: Article (author)

Files in This Item:

There are no files associated with this item.


SFX Query


Items in AIR are protected by copyright, with all rights reserved, unless otherwise indicated.


Share this record with your
favourite social network:

Del.icio.us

Citeulike

Connotea

Facebook

Stumble it!

reddit

mendeley


 

  Browser supportati Firefox 3+, Internet Explorer 7+, Google Chrome, Safari

ICT Support, development & maintenance are provided by CINECA. Powered on DSpace Software.
CINECA