The reproductive history was analyzed of 13 women with a laparoscopic or laparotomy diagnosis of uterus didelphys and followed for two to six years. Two patients (15.4%) presented with primary infertility; the other 11 had a total of 27 pregnancies, the outcome of which was spontaneous abortion in 20 cases (74%), premature labor in 6 (22.2%) and term birth in 1 (3.7%), with a live birth rate of 18.5%. Metroplasty was performed in five cases, with live birth in three, spontaneous abortion in 1 and no postoperative conceptions in one. Cervical cerclage was performed in only one case and bilateral ovarian resection in one. The live birth rate, considering all pregnancies before and after treatment, was 35%. The compromised fertility of the uterus didelphys is probably attributable to congenital alterations in vascularization that may have a negative influence on developmental phases following implantation, particularly the structuralization of the fetomaternal relations that precede placentation.

Gestational aspects of uterus didelphys / L. Fedele, D. Zamberletti, A. D'Alberton, P. Vercellini, G.B. Candiani. - In: JOURNAL OF REPRODUCTIVE MEDICINE. - ISSN 0024-7758. - 33:4(1988 Apr), pp. 353-355.

Gestational aspects of uterus didelphys

L. Fedele
Primo
;
P. Vercellini
Penultimo
;
1988

Abstract

The reproductive history was analyzed of 13 women with a laparoscopic or laparotomy diagnosis of uterus didelphys and followed for two to six years. Two patients (15.4%) presented with primary infertility; the other 11 had a total of 27 pregnancies, the outcome of which was spontaneous abortion in 20 cases (74%), premature labor in 6 (22.2%) and term birth in 1 (3.7%), with a live birth rate of 18.5%. Metroplasty was performed in five cases, with live birth in three, spontaneous abortion in 1 and no postoperative conceptions in one. Cervical cerclage was performed in only one case and bilateral ovarian resection in one. The live birth rate, considering all pregnancies before and after treatment, was 35%. The compromised fertility of the uterus didelphys is probably attributable to congenital alterations in vascularization that may have a negative influence on developmental phases following implantation, particularly the structuralization of the fetomaternal relations that precede placentation.
Uterus ; Fertility ; Prospective Studies ; Infertility, Female ; Humans ; Adult ; Retrospective Studies ; Prognosis ; Female ; Pregnancy ; Pregnancy Outcome
Settore MED/40 - Ginecologia e Ostetricia
apr-1988
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/206214
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