Exposure to UV radiation is associated with cutaneous malignant melanoma (CMM). In mammalian cells, UV radiation induces DNA damage that can be repaired by the nucleotide excision repair system. We designed this case-control study to determine whether DNA repair capacity (DRC) is associated with the risk of CMM and to identify risk factors that may interact biologically with DRC in the development of melanoma.

DNA repair, dysplastic nevi, and sunlight sensitivity in the development of cutaneous malignant melanoma / M.T. Landi, A. Baccarelli, R.E. Tarone, A. Pesatori, M.A. Tucker, M. Hedayati, L. Grossman. - In: JOURNAL OF THE NATIONAL CANCER INSTITUTE. - ISSN 0027-8874. - 94:2(2002 Jan 16), pp. 94-101.

DNA repair, dysplastic nevi, and sunlight sensitivity in the development of cutaneous malignant melanoma

A. Baccarelli
Secondo
;
A. Pesatori;
2002

Abstract

Exposure to UV radiation is associated with cutaneous malignant melanoma (CMM). In mammalian cells, UV radiation induces DNA damage that can be repaired by the nucleotide excision repair system. We designed this case-control study to determine whether DNA repair capacity (DRC) is associated with the risk of CMM and to identify risk factors that may interact biologically with DRC in the development of melanoma.
DNA Repair ; Skin ; Humans ; Aged ; Skin Neoplasms ; Dysplastic Nevus Syndrome ; Likelihood Functions ; Melanoma ; Risk Factors ; Adult ; Case-Control Studies ; Sunlight ; Middle Aged ; Female ; Male
Settore MED/44 - Medicina del Lavoro
16-gen-2002
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/204195
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