A new one-pot approach was developed to construct the 11H-indolo[3,2-c]quinoline scaffold through a gold-catalysed reaction of 2-[(2-aminophenyl)ethynyl]phenylamine derivatives with aldehydes. The broad scope and the high regioselectivity of this new protocol as well as the mild and neutral reaction conditions make it a viable alternative to the previously reported procedures.
An alternative one-pot gold-catalyzed approach to the assembly of 11H-indolo[3,2-c]quinolines / G. Abbiati, A. Arcadi, M. Chiarini, F. Marinelli, E. Pietropaolo, E. Rossi. - In: ORGANIC & BIOMOLECULAR CHEMISTRY. - ISSN 1477-0520. - 10:38(2012 Sep), pp. 7801-7808.
An alternative one-pot gold-catalyzed approach to the assembly of 11H-indolo[3,2-c]quinolines
G. AbbiatiPrimo
;E. RossiUltimo
2012
Abstract
A new one-pot approach was developed to construct the 11H-indolo[3,2-c]quinoline scaffold through a gold-catalysed reaction of 2-[(2-aminophenyl)ethynyl]phenylamine derivatives with aldehydes. The broad scope and the high regioselectivity of this new protocol as well as the mild and neutral reaction conditions make it a viable alternative to the previously reported procedures.
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