A population of 1,087 blood donors underwent anti-HTLV-I/II screening carried out by means of two different ELISA tests. Eleven of them showed reactivity to one of the two kits employed; after Western Blotting (WB), only one resulted positive: the others were either undeterminate (7) or negative (3). PCR for the detection of HTLV-DNA was performed on a sample of Peripheral Blood Mononuclear Cells (PBMC): the result was positive for all WB positive and undeterminate subjects. These data suggest that prevalence of HTLV-I/II infection in blood donors may be understimated.
Donatori di sangue con infezione da HTLV-I/II e Western blot indeterminato / M. Girotto, G. Zehender, G. Francisco, C. DE MADDALENA, M. Galli. - In: BLOOD TRANSFUSION. - ISSN 1723-2007. - 42:6(1997), pp. 341-342.
Donatori di sangue con infezione da HTLV-I/II e Western blot indeterminato
G. ZehenderSecondo
;M. GalliUltimo
1997
Abstract
A population of 1,087 blood donors underwent anti-HTLV-I/II screening carried out by means of two different ELISA tests. Eleven of them showed reactivity to one of the two kits employed; after Western Blotting (WB), only one resulted positive: the others were either undeterminate (7) or negative (3). PCR for the detection of HTLV-DNA was performed on a sample of Peripheral Blood Mononuclear Cells (PBMC): the result was positive for all WB positive and undeterminate subjects. These data suggest that prevalence of HTLV-I/II infection in blood donors may be understimated.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
