The time evolution of native bonds formation probability was studied for designed sequences which fold fast into the native conformation. The native bonds formed was classified into three groups. These are: local, fast forming highly stable native bonds produced from strongly interacting amino acid of the protein; nonlocal bonds formed late in the folding process simultaneously with the folding nucleus and has essentially similar strongly interacting amino acids already found in the fast bonds; and the rest of the native bonds which are subordinate, to a large extent, to that of the strong local and nonlocal native contacts.

Statistical Analysis of Native Contact Formation in the Folding of Designed Model Proteins / g. tiana, r. a. broglia. - In: THE JOURNAL OF CHEMICAL PHYSICS. - ISSN 0021-9606. - 114:5(2001), pp. 2503-2510.

Statistical Analysis of Native Contact Formation in the Folding of Designed Model Proteins

g. tiana
Primo
;
2001

Abstract

The time evolution of native bonds formation probability was studied for designed sequences which fold fast into the native conformation. The native bonds formed was classified into three groups. These are: local, fast forming highly stable native bonds produced from strongly interacting amino acid of the protein; nonlocal bonds formed late in the folding process simultaneously with the folding nucleus and has essentially similar strongly interacting amino acids already found in the fast bonds; and the rest of the native bonds which are subordinate, to a large extent, to that of the strong local and nonlocal native contacts.
Settore FIS/03 - Fisica della Materia
2001
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/194143
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