Six lambs, where extracorporeal blood flow ranging between 600 and 1000 ml min-1 was continuously maintained, were mechanically ventilated in two different modes: continuous positive pressure ventilation (CPPV) with 5 cm H2O PEEP and low frequency positive pressure ventilation with 5 cm H2O PEEP and extracorporeal CO2 removal through a carbon dioxide membrane lung (LEPPV-ECCO2R). The blood gases were in normal ranges through both CPPV and LFPPV-ECCO2R, even if a higher PaO2 was found during CPPV. However, during LFPPV-ECCO2R, cardiac output increased about 30%, O2 transport 19.3%, while heart rate, pulmonary artery pressure and arterial pressure did not change. LFPPV-ECCO2R, in the experiments, seems to overcome some hemodynamic impairments of CPPV.
Risposte emodinamiche durante ventilazione a pressione positiva continua a bassa frequenza con rimozione extracorporea di CO2 (LLFPPV-ECCO2R.) : studio comparativo rispetto alla ventilazione a pressione positiva continua (CPPV) / A. Pelizzola, L. Gattinoni, G.P. Rossi, C. Berrini, R. Fassina, G. Iacono, C. Bernasconi, M. Bedoni, D. Cantaluppi. - In: ANESTESIA E RIANIMAZIONE. - ISSN 0570-0760. - 19:4(1978), pp. 303-315.
Risposte emodinamiche durante ventilazione a pressione positiva continua a bassa frequenza con rimozione extracorporea di CO2 (LLFPPV-ECCO2R.) : studio comparativo rispetto alla ventilazione a pressione positiva continua (CPPV)
L. GattinoniSecondo
;
1978
Abstract
Six lambs, where extracorporeal blood flow ranging between 600 and 1000 ml min-1 was continuously maintained, were mechanically ventilated in two different modes: continuous positive pressure ventilation (CPPV) with 5 cm H2O PEEP and low frequency positive pressure ventilation with 5 cm H2O PEEP and extracorporeal CO2 removal through a carbon dioxide membrane lung (LEPPV-ECCO2R). The blood gases were in normal ranges through both CPPV and LFPPV-ECCO2R, even if a higher PaO2 was found during CPPV. However, during LFPPV-ECCO2R, cardiac output increased about 30%, O2 transport 19.3%, while heart rate, pulmonary artery pressure and arterial pressure did not change. LFPPV-ECCO2R, in the experiments, seems to overcome some hemodynamic impairments of CPPV.Pubblicazioni consigliate
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