Università degli Studi di Milano   Archivio Istituzionale della Ricerca
Please use this identifier to cite or link to this item: http://hdl.handle.net/2434/185474

Title: Effect of 5 alpha-reduced androgens on prolactin secretion
Authors: CELOTTI, FABIO MARIA (First author)
NEGRI CESI, PAOLA (Second to last author)
MOTTA, MARCELLA (Last author)
Abstract: The effects of a 6-day treatment with 2 mg/day of testosterone, dihydrotestosterone (DHT), 5 alpha-androstan-3 alpha, 17 beta-diol (3 alpha-diol) and 5 alpha-androstan-3 beta, 17 beta-diol (3 beta-diol) on serum prolactin levels have been evaluated in long-term castrated male and female rats. The steroids were administered either in the free alcohol or in the propionated form (mono and dipropionates for the 3 alpha- and 3 beta-diols). Practically no effect of any steroid was evident in the treated male animals. DHT and 3 alpha-diol inhibited prolactin secretion in the female animals, while testosterone and 3 beta-diol remained ineffective. The data suggest a possible role of 5 alpha-reduced compounds, DHT and 3 alpha-diol in the control of prolactin secretion in females.
Keywords: Rats, Inbred Strains; Rats; Prolactin; Animals; Dihydrotestosterone; Androstane-3,17-diol; Male; Female; Androgens
MIUR subjects: MED/04 - Patologia Generale
BIO/09 - Fisiologia
Publication date: 1982
Citation: Effect of 5 alpha-reduced androgens on prolactin secretion / F. Celotti, N. Avogadri, P. Negri-Cesi, M. Motta. - In: Andrologia. - ISSN 0303-4569. - 14:6(1982), pp. 526-531.
Pubmed identifier: 7165125
Type: Article (author)

Files in This Item:

There are no files associated with this item.


SFX Query


Items in AIR are protected by copyright, with all rights reserved, unless otherwise indicated.


Share this record with your
favourite social network:

Del.icio.us

Citeulike

Connotea

Facebook

Stumble it!

reddit


 

  Browser supportati Firefox 3+, Internet Explorer 7+, Google Chrome, Safari

ICT Support, development & maintenance are provided by CINECA. Powered on DSpace Software.
CINECA