Receptor concentrations for adrenaline, steroid hormones, PGF(2 alpha), LH and FSH were measured in the hypophysis and ovary of dairy cows with ovarian cysts and the results were compared with those of healthy animals. Significant modifications were found in all receptor concentrations, either between follicular and luteal structures or between the hypophyseal and ovarian receptorial status. The correlations between catecholaminergic and steroidal systems have already been demonstrated, particularly those existing between p-adrenoceptors and steroid hormone receptors. Particular attention has been given to the possibility that a derangement in neurogenic inputs may be at the basis of some ovarian pathologies. The results of the present study suggest that the modifications of the ovarian and hypophyseal receptorial status of healthy and affected cows could play an important role in the pathogenesis of ovarian cysts.
Modifications of receptor concentrations for adrenaline, steroid hormones, prostaglandin F-2 alpha and gonadotropins in hypophysis and ovary of dairy cows with ovarian cysts / R. Odore, G. Re, P. Badino, A. Donn, D. Vigo, B. Biolatti, C. Girardi. - In: PHARMACOLOGICAL RESEARCH. - ISSN 1043-6618. - 39:4(1999), pp. 297-304.
Modifications of receptor concentrations for adrenaline, steroid hormones, prostaglandin F-2 alpha and gonadotropins in hypophysis and ovary of dairy cows with ovarian cysts
D. Vigo;
1999
Abstract
Receptor concentrations for adrenaline, steroid hormones, PGF(2 alpha), LH and FSH were measured in the hypophysis and ovary of dairy cows with ovarian cysts and the results were compared with those of healthy animals. Significant modifications were found in all receptor concentrations, either between follicular and luteal structures or between the hypophyseal and ovarian receptorial status. The correlations between catecholaminergic and steroidal systems have already been demonstrated, particularly those existing between p-adrenoceptors and steroid hormone receptors. Particular attention has been given to the possibility that a derangement in neurogenic inputs may be at the basis of some ovarian pathologies. The results of the present study suggest that the modifications of the ovarian and hypophyseal receptorial status of healthy and affected cows could play an important role in the pathogenesis of ovarian cysts.Pubblicazioni consigliate
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