The effects of cortisone acetate injected i.p. on acid phosphatase and beta-glucuronidase in the small intestine mucosa of two groups of rats aging 12-14 and 20-22 days are reported. The following results are obtained: a) Total and free activities of the two enzymes show age-dependent differences. b) Cortisone acetate causes a very marked decrease of the enzymic activities only in the younger rats while being ineffective on the older ones. c) The kinetics of the enzyme release at 37 degrees C appear independent either of age or of cortisone injection. d) The "in vitro" lysosome labilizing treatments are ineffective.
Influence of age and cortisone treatment on two intestinal lysosomal hydrolases in young rats / T. Baglioni, A. Locatelli, P. Sartorelli, T. Simonic. - In: ITALIAN JOURNAL OF BIOCHEMISTRY. - ISSN 0021-2938. - 27:1(1978), pp. 1-10.
Influence of age and cortisone treatment on two intestinal lysosomal hydrolases in young rats
P. SartorelliPenultimo
;T. SimonicUltimo
1978
Abstract
The effects of cortisone acetate injected i.p. on acid phosphatase and beta-glucuronidase in the small intestine mucosa of two groups of rats aging 12-14 and 20-22 days are reported. The following results are obtained: a) Total and free activities of the two enzymes show age-dependent differences. b) Cortisone acetate causes a very marked decrease of the enzymic activities only in the younger rats while being ineffective on the older ones. c) The kinetics of the enzyme release at 37 degrees C appear independent either of age or of cortisone injection. d) The "in vitro" lysosome labilizing treatments are ineffective.
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