An efficient protocol for the 4 beta-acylamidation of the N-acylated glycals of Neu5Ac by using the corresponding N-perfluoroacylated congeners as key tools has been developed and applied to the synthesis of glycals combining the features of the molecules with antiviral properties.
Facile Diastereoselective Entry to 4 beta-Acylamidation of Neu5Ac2en Glycals Using Their N-Perfluoroacylated Congeners as Key Tools / P. Rota, I. Agnolin, P. Allevi, M. Anastasia. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - 2012:13(2012), pp. 2508-2510. [10.1002/ejoc.201200151]
Facile Diastereoselective Entry to 4 beta-Acylamidation of Neu5Ac2en Glycals Using Their N-Perfluoroacylated Congeners as Key Tools
P. RotaPrimo
;I. AgnolinSecondo
;P. AlleviPenultimo
;M. AnastasiaUltimo
2012
Abstract
An efficient protocol for the 4 beta-acylamidation of the N-acylated glycals of Neu5Ac by using the corresponding N-perfluoroacylated congeners as key tools has been developed and applied to the synthesis of glycals combining the features of the molecules with antiviral properties.
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