Restriction enzymes analysis of the DNA from two unrelated Italian families with Hb Hasharon, a variant Hb (alpha 47asp replaced by his) frequently occurring in the Polesine area in Italy, indicates that this variant is associated to an alpha globin gene deletion. The alpha Hash genotype most likely results from a mutation on an alpha thal2 genotype

Organization of alpha-globin genes in Hb Hasharon (alpha 47 asp replaced by his) carriers / B. Giglioni, P. Comi, R. Taramelli, S. Ottolenghi, M.A. Ciocca Vasino, C. Anè, M.D. Cappellini, A.M. Gianni. - In: BLOOD. - ISSN 0006-4971. - 56:6(1980 Dec), pp. 1145-1149.

Organization of alpha-globin genes in Hb Hasharon (alpha 47 asp replaced by his) carriers

M.D. Cappellini;A.M. Gianni
1980

Abstract

Restriction enzymes analysis of the DNA from two unrelated Italian families with Hb Hasharon, a variant Hb (alpha 47asp replaced by his) frequently occurring in the Polesine area in Italy, indicates that this variant is associated to an alpha globin gene deletion. The alpha Hash genotype most likely results from a mutation on an alpha thal2 genotype
Globins ; Chromosome Deletion ; DNA Restriction Enzymes ; Heterozygote Detection ; Genes ; Humans ; Histidine ; Hemoglobins, Abnormal ; Thalassemia ; Asparagine ; Italy
Settore MED/06 - Oncologia Medica
dic-1980
http://bloodjournal.hematologylibrary.org/content/56/6/1145.long
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/176036
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