Pharmacologically interesting trans beta-lactones 11 and 16 were synthesized using a titanium tetrachloride-mediated enantioselective aldol reaction as the key synthetic step (see Scheme 2).
TITANIUM TETRACHLORIDE-MEDIATED ENANTIOSELECTIVE SYNTHESIS OF TRANS BETA-LACTONES / S. CARDANI, C. DETOMA, C.M.A. GENNARI, C. SCOLASTICO. - In: TETRAHEDRON. - ISSN 0040-4020. - 48:27(1992), pp. 5557-5564. [10.1016/S0040-4020(01)90133-4]
TITANIUM TETRACHLORIDE-MEDIATED ENANTIOSELECTIVE SYNTHESIS OF TRANS BETA-LACTONES
C.M.A. GennariPenultimo
;C. ScolasticoUltimo
1992
Abstract
Pharmacologically interesting trans beta-lactones 11 and 16 were synthesized using a titanium tetrachloride-mediated enantioselective aldol reaction as the key synthetic step (see Scheme 2).
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