The hydrogen phthalate of isopropylidene glycerol has been recently described as an efficient resolving agent of 1-arylethylamines. In order to gain more information on its versatility and to develop a rationale which accounts for its effectiveness, further 1-arylethylamines and other racemic amines were subjected to the same resolution process. A preliminary qualitative analysis of the results reported herein allows to identify some structural features of the aminic substrates conditioning the feasibility of the resolution.
Resolution of amines with isopropylidene glycerol hydrogen phthalate / M. Pallavicini, E. Valoti, L. Villa, O. Piccolo. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - 8:7(1997), pp. 1069-1073. [10.1016/S0957-4166(97)00089-X]
Resolution of amines with isopropylidene glycerol hydrogen phthalate
M. PallaviciniPrimo
;E. ValotiSecondo
;
1997
Abstract
The hydrogen phthalate of isopropylidene glycerol has been recently described as an efficient resolving agent of 1-arylethylamines. In order to gain more information on its versatility and to develop a rationale which accounts for its effectiveness, further 1-arylethylamines and other racemic amines were subjected to the same resolution process. A preliminary qualitative analysis of the results reported herein allows to identify some structural features of the aminic substrates conditioning the feasibility of the resolution.Pubblicazioni consigliate
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