The science of genomes: only within the past few decades have scientists progressed from the analysis of a single or a small number of genes at once to the investigation of thousands of genes, going from the study of the units of inheritance to the investigation of the whole genome of an organism. The science of the genomes, or "genomics," initially dedicated to the determination of DNA sequences (the nucleotide order on a given fragment of DNA), has promptly expanded toward a more functional level--studying the expression profiles and the roles of both genes and proteins. The aim of the chapter is to review some basic assumptions and definitions that are the fabric of genomics, and to elucidate key concepts and approaches on which genomics rely

Introduction to genomics / L. Del Giacco, C. Cattaneo - In: Molecular profiling / [a cura di] V. Espina, L.A. Liotta. - New York : Humana press, 2012. - ISBN 9781603272155. - pp. 79-88

Introduction to genomics

L. Del Giacco
Primo
;
C. Cattaneo
2012

Abstract

The science of genomes: only within the past few decades have scientists progressed from the analysis of a single or a small number of genes at once to the investigation of thousands of genes, going from the study of the units of inheritance to the investigation of the whole genome of an organism. The science of the genomes, or "genomics," initially dedicated to the determination of DNA sequences (the nucleotide order on a given fragment of DNA), has promptly expanded toward a more functional level--studying the expression profiles and the roles of both genes and proteins. The aim of the chapter is to review some basic assumptions and definitions that are the fabric of genomics, and to elucidate key concepts and approaches on which genomics rely
Animals ; Chromosome Mapping ; Computational Biology ; Genome/genetics ; Genomics/methods ; Sequence Analysis
Settore BIO/11 - Biologia Molecolare
2012
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/175611
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