The synthesis of a number of novel simplified eleutheside analogues with potent tubulin-assembling and microtubulestabilizing properties is described, using ring-closing metathesis as the key-step for obtaining the 6-10 fused bicyclic ring system. (C) 2003 Elsevier Science Ltd. All rights reserved.
Synthesis of novel simplified eleutheside analogues with potent microtubule-stabilizing activity, using ring-closing metathesis as the key-step / R. Beumer, J.P. Bayon Rueda, P. Bugada, S. Ducki, N. Mongelli, F. Sirtori, J. Telser, C.M.A. Gennari. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 44:4(2003 Jan 20), pp. 681-684.
Synthesis of novel simplified eleutheside analogues with potent microtubule-stabilizing activity, using ring-closing metathesis as the key-step
J.P. Bayon RuedaSecondo
;C.M.A. GennariUltimo
2003
Abstract
The synthesis of a number of novel simplified eleutheside analogues with potent tubulin-assembling and microtubulestabilizing properties is described, using ring-closing metathesis as the key-step for obtaining the 6-10 fused bicyclic ring system. (C) 2003 Elsevier Science Ltd. All rights reserved.File in questo prodotto:
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