Although most preservation solutions as well as some cardioplegic solutions used for organ storage and transplantation are hypertonic, the effects of extracellular hypertonicity on endothelium are not well established. Aims of this study were to evaluate the response of cultured human saphenous vein endothelial cells to extracellular hypertonicity and to investigate the role of the amino acid glutamine in preventing endothelial damage in vitro.
Hypertonicity induces injury to cultured human endothelium: attenuation by glutamine / A. Parolari, R. Sala, C. Antona, O. Bussolati, F. Alamanni, P. Mezzadri, V. Dall’Asta, G.C. Gazzola, P. Biglioli. - In: ANNALS OF THORACIC SURGERY. - ISSN 0003-4975. - 64:6(1997 Dec), pp. 1770-1775. [10.1016/S0003-4975(97)00998-3]
Hypertonicity induces injury to cultured human endothelium: attenuation by glutamine
A. ParolariPrimo
;C. Antona;F. Alamanni;P. BiglioliUltimo
1997
Abstract
Although most preservation solutions as well as some cardioplegic solutions used for organ storage and transplantation are hypertonic, the effects of extracellular hypertonicity on endothelium are not well established. Aims of this study were to evaluate the response of cultured human saphenous vein endothelial cells to extracellular hypertonicity and to investigate the role of the amino acid glutamine in preventing endothelial damage in vitro.
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